Nanobiotechnology approaches for miniaturized diagnostics

Outlook of various diagnostics and nanodiagnostic techniques for COVID-19

“…Nanodiagnostic tools are advanced diagnostic devices developed by integrating nanotechnology with biomedical engineering. The development of nanotechnology-based diagnostic devices has revolutionized the medical field with the introduction of miniaturized diagnostics ( Borse et al, 2020a , 2020b , 2022 ; Borse and Srivastava, 2019 , 2020 ; Kaur et al, 2021 ; Konwar and Borse, 2020 ; Roy et al, 2022 ). Fig.…”

“…The advantages of nanodiagnostic devices can be attributed to the unique features of the constituent nanomaterial. The use of nanobiosensors for developing diagnostic devices is favored by several benefits, such as a low LOD, ease of use, quicker diagnosis, and possible miniaturization ( Borse and Srivastava, 2020 ; Borse et al, 2020b ). In this way, the use of nanomaterials favors the development of POC diagnostic devices.…”

Affinity-Based Nanoarchitectured Biotransducer for Sensitivity Enhancement of Surface Plasmon Resonance Sensors for In Vitro Diagnosis: A Review

“…However, the scientific fraternity has been exploring the application of AuNPs or their conjugated forms and biotransducers to in vitro diagnosis of various health-related major concerns, such as cancer biosensing, diabetes mellitus, thrombin detection, etc. The AgNPs offer notable merits, including high conductivity, excellent biocompatibility, and amplified electrochemical signal . Because of notable advantages of AgNPs-based sensor platforms, AgNPs exhibit a major impact on biomedical applications.…”

“…The AgNPs offer notable merits, including high conductivity, excellent biocompatibility, and amplified electrochemical signal. 79 Because of notable advantages of AgNPs-based sensor platforms, AgNPs exhibit a major impact on biomedical applications. Moreover, across current two decades, much emphasis has been directed to developing innovative approaches for assorted targets of interest, including identification of disease/disorder biomarkers, as well as bioinfectious molecules based on nanomodified AgNPs/ composites at the early stage of disease or disorders.…”