Nanocelluloses From Sugarcane Biomass

Pereira, Bárbara; Arantes, Valdeir

doi:10.1016/b978-0-12-804534-3.00009-4

Cited by 25 publications

(18 citation statements)

References 74 publications

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“…143 Also, the energy consumption of disk refiners is lower than the homogenizer and microfluidizer. 144 Therefore, optimizing the energy consumption of a mechanical technique is important in reducing the cost of production.…”

Section: ■ Introductionmentioning

confidence: 99%

“…This could be due to the generation of periodic compression forces in a Valley beater that improves the straightening of fibers . Also, the energy consumption of disk refiners is lower than the homogenizer and microfluidizer . Therefore, optimizing the energy consumption of a mechanical technique is important in reducing the cost of production.…”

Section: Introductionmentioning

confidence: 99%

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Production of Nanocellulose and Its Applications in Drug Delivery: A Critical Review

Salimi

Sotudeh‐Gharebagh

Zarghami

et al. 2019

ACS Sustainable Chem. Eng.

211

116

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Nanocellulose, as a promising natural material, has recently received much attention because of its remarkable features including recyclability, biocompatibility, low risk of toxicity, and tunable surface properties. This review article first introduces three types of nanocellulose (nanocrystalline, nanofibrillar, and bacterial) and evaluates their production processes. In addition, contemporary research is discussed in the formulations of nanoparticles, tablets, hydrogels, and aerogels. As reported in the literature, the release time of nanocellulose-based systems varies from a few minutes to several days as they provide a controlled and sustained release. Thus, such systems have shown considerable potential for developing a novel generation of controlled drug delivery for different routes of administration (oral, transdermal, etc.). This review facilitates the selection of proper source and processing techniques for nanocellulose production while addressing opportunities and challenges ahead ending up with identifying sustainable ongoing research directions into its applications in drug delivery.

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Section: ■ Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Production of Nanocellulose and Its Applications in Drug Delivery: A Critical Review

Salimi

Sotudeh‐Gharebagh

Zarghami

et al. 2019

ACS Sustainable Chem. Eng.

211

116

View full text Add to dashboard Cite

show abstract

“…By addition of water, interruption of the hydrolytic reactions, to remove acid extensive dialysis, is done. For dispersion of particles, mechanical treatment by sonication is done, and uniform and stable suspension is obtained; after that it is dried when the solid CNC is required [265]. These are needle-shaped materials that get fitted into the ocular microfibrils when their amorphous sites get destroyed [266].…”

Section: Cellulose Nanocrystalsmentioning

confidence: 99%

Cellulosic Polymers for Enhancing Drug Bioavailability in Ocular Drug Delivery Systems

et al. 2021

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One of the major impediments to drug development is low aqueous solubility and thus poor bioavailability, which leads to insufficient clinical utility. Around 70–80% of drugs in the discovery pipeline are suffering from poor aqueous solubility and poor bioavailability, which is a major challenge when one has to develop an ocular drug delivery system. The outer lipid layer, pre-corneal, dynamic, and static ocular barriers limit drug availability to the targeted ocular tissues. Biopharmaceutical Classification System (BCS) class II drugs with adequate permeability and limited or no aqueous solubility have been extensively studied for various polymer-based solubility enhancement approaches. The hydrophilic nature of cellulosic polymers and their tunable properties make them the polymers of choice in various solubility-enhancement techniques. This review focuses on various cellulose derivatives, specifically, their role, current status and novel modified cellulosic polymers for enhancing the bioavailability of BCS class II drugs in ocular drug delivery systems.

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“…Numerous studies have demonstrated the possibility of obtaining cellulose nanofibers, nanocrystals, or nanofibrils from non-conventional cellulose resources (Oun and Rhim, 2016;Bajpai, 2017;Chen and Lee, 2018;Pereira and Arantes, 2018). Reddy et al(Reddy and Rhim, 2014) demonstrated that paper-mulberry (Broussonetia kazinoki Siebold) bast pulp could be used as a new, environmentally friendly nanocellulose source.…”

Section: Introductionmentioning

confidence: 99%

Cytocompatible cellulose nanofibers from invasive plant species Agave americana L. and Ricinus communis L.: a renewable green source of highly crystalline nanocellulose

Евдокимова

Alves

Whiffen

et al. 2021

J. Zhejiang Univ. Sci. B

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In this study, the fibers of invasive species Agave americana L. and Ricinus communis L. were successfully used for the first time as new sources to produce cytocompatible and highly crystalline cellulose nanofibers. Cellulose nanofibers were obtained by two methods, based on either alkaline or acid hydrolysis. The morphology, chemical composition, and crystallinity of the obtained materials were characterized by scanning electron microscopy (SEM) together with energy-dispersive X-ray spectroscopy (EDX), dynamic light scattering (DLS), X-Ray diffraction (XRD), and FTIR-spectroscopy. The crystallinity index (CI) of the cellulose nanofibers extracted from Agave americana L. and Ricinus communis L. was very high: 94% and 92.7%, respectively. Biological studies evaluating the cytotoxic effects of the prepared cellulose nanofibers on HEK 293T cells were also performed. The nanofibers obtained using the two different extraction methods were all shown to be cytocompatible in the concentration range assayed (i.e., 0-500 µg/mL). Our results showed that the nanocellulose extracted from Agave americana L. and Ricinus communis L. fibers has high potential as a new renewable, green source of highly crystalline cellulose-based cytocompatible nanomaterials for biomedical applications.

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Nanocelluloses From Sugarcane Biomass

Cited by 25 publications

References 74 publications

Production of Nanocellulose and Its Applications in Drug Delivery: A Critical Review

Production of Nanocellulose and Its Applications in Drug Delivery: A Critical Review

Cellulosic Polymers for Enhancing Drug Bioavailability in Ocular Drug Delivery Systems

Cytocompatible cellulose nanofibers from invasive plant species Agave americana L. and Ricinus communis L.: a renewable green source of highly crystalline nanocellulose

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