Nanocomplexes of curcumin and glycated bovine serum albumin: The formation mechanism and effect of glycation on their physicochemical properties

Phosphorylated walnut protein isolate as a nanocarrier for enhanced water solubility and stability of curcumin

“…The zeta potential of the nanocomplexes was approximately −38 mV. High surface charges can provide sufficient repulsion force and facilitate the stabilization of the nanocomplex 56 …”

Glycated α-lactalbumin based micelles for quercetin delivery: Physicochemical stability and fate of simulated digestion

“…This result indicated that micelles with higher EE had better effect to mask the characteristic peaks of quercetin. In addition, when quercetin was incorporated into the micelles, the peaks in the coat materials assigned with hydroxy stretching vibrations moved from 3303, 3303, 3286, 3306, 3401 cm −1 (ALA, Mai 1:1, Mai 1:2, Mai 1:4 and Mix 1:4) to 3309, 3401, 3402, 3401, 3397 cm −1 (ALA-Q, Mai 1:1-Q, Mai 1:2-Q, Mai 1:4-Q and Mix 1:4-Q), respectively, confirming the presence of hydrogen bonding between quercetin and the coat materials ( Fu et al, 2022 ). Moreover, the shift of the peaks from 1648, 1666, 1658, 1660 and 1652 cm −1 to 1662, 1660, 1659, 1657 and 1659 cm −1 (amide I, C—O stretching), and 1083, 1110, 1113, 1111 and 1107 cm −1 to 1165, 1158, 1157, 1153 and 1158 cm −1 (C—O—C stretching) in the nutraceutical loaded biopolymer micelles were consistent with hydrophobic interactions among the ALA and quercetin ( Chen et al, 2020 ).…”

“…Protein glycation has been considered as a promising strategy to improve the functional properties of natural proteins, which is based on the initial stage of the Maillard reaction taken place between the amino groups in proteins and the carbonyl groups in reducing carbohydrates ( Liu, Ma, Gao, & Mcclements, 2017 ). After glycated with polysaccharide, the formed conjugates possess excellent amphiphilicity to encapsulate lipophilic bioactive compounds such as lutein, resveratrol, curcumin, β-carotene and astaxanthin ( Davidov-Pardo et al, 2015 , Fu et al, 2022 , Kim and Shin, 2021 , Xu et al, 2014 , Zhang et al, 2021 ). Furthermore, studies have shown that delivery systems comprised of proteins-polysaccharide conjugates had controlled release effect in simulated gastrointestinal digestion ( Zhang, Zhou, et al, 2021 ).…”

Fabrication, physicochemical stability and gastrointestinal fate of curcumin‐loaded nanoemulsions stabilised by bovine serum albumin‐glucose conjugates with different degree of glycation

“…The stability of the nanoemulsion was assessed by measuring the Z‐average diameter, zeta potential, microstructure and macroscopic appearance under harsh environmental conditions according to the method described in our previous study (Fu et al ., 2022).…”