Nanocomposite of cosubstituted carbonated hydroxyapatite fabricated inside Poly(sodium hyaluronate-acrylamide) hydrogel template prepared by gamma radiation for osteoblast cell regeneration

El-Sayyad, Gharieb S.; El‐Sawy, Naeem M.; Kodous, Ahmad S.

doi:10.1016/j.radphyschem.2021.109408

Cited by 39 publications

(25 citation statements)

References 90 publications

(84 reference statements)

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“…While the peaks at 2931 and 2783 cm −1 ascribed to the C–H asymmetrical stretching and vibrations in methyl and methylene structures, respectively 29 . And the peak at 1675 cm −1 is assigned to the C=O stretching vibrations 30 . Compared with PAM hydrogel, AL‐0 composite hydrogel has characteristic peaks of CMX at 1601 and 920 cm −1 , which attribute to the presence of the COO − group 31 and arabinose units, 32 respectively.…”

Section: Resultsmentioning

confidence: 99%

“…29 And the peak at 1675 cm À1 is assigned to the C=O stretching vibrations. 30 Compared with PAM hydrogel, AL-0 composite hydrogel has characteristic peaks of CMX at 1601 and 920 cm À1 , which attribute to the presence of the COO À group 31 and arabinose units, 32 respectively. In the spectrum of AL-3.7 composite hydrogel, an increase in peak intensity at 1601 and 1422 cm À1 corresponds to the stretching vibration of the benzene ring skeleton.…”

Section: Resultsmentioning

confidence: 99%

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A green composite hydrogel based on xylan and lignin with adjustable mechanical properties, high swelling, excellent UV shielding, and antioxidation properties

Wang

et al. 2022

J of Applied Polymer Sci

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This study successfully prepared a novel green composite hydrogel based on carboxymethyl xylan and lignin with adjustable mechanical properties, high swelling, excellent UV shielding, and antioxidation performance. The structure and morphology of the hydrogel were characterized by Fourier transform infrared spectra, scanning electron microscopy, thermogravimetric analysis, rheological analysis, and swelling ratio. Results showed that lignin could significantly improve the mechanical properties of composite hydrogels. The compression stress and toughness of the composite hydrogel contained lignin increased by 39% and 60%, respectively, and the compressive deformation reached 90%. In addition, the addition of lignin increased the swelling ratio of the composite hydrogel reached 79.9 g/g. In addition, the composite hydrogel exhibited excellent UV shielding and antioxidation performance. The removal ratio of UV and free radicals is as high as 80% and 90%, respectively. The simple procedure and cost‐effective lignin as raw material for hydrogel with adjustable properties are favorable for medical‐biological applications.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

A green composite hydrogel based on xylan and lignin with adjustable mechanical properties, high swelling, excellent UV shielding, and antioxidation properties

Wang

et al. 2022

J of Applied Polymer Sci

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“…The hydrogel acted as a HA template and carbon precursor. In vitro studies demonstrated that using this hydrogel as a biocompatible nanomaterial improved osteogenic ability compared with HA [ 120 ]. Davidenko et al prepared collagen- and gelatin-based scaffolds crosslinked through UV irradiation (λ = 254 nm) to modulate the materials’ properties while keeping their biological functionality [ 121 ].…”

Section: Crosslinking Methods and Agents In Ha-based Composite Scaffoldsmentioning

confidence: 99%

Recent Advances in Hydroxyapatite-Based Biocomposites for Bone Tissue Regeneration in Orthopedics

Ielo

Calabrese

Luca

et al. 2022

IJMS

178

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Bone tissue is a nanocomposite consisting of an organic and inorganic matrix, in which the collagen component and the mineral phase are organized into complex and porous structures. Hydroxyapatite (HA) is the most used ceramic biomaterial since it mimics the mineral composition of the bone in vertebrates. However, this biomimetic material has poor mechanical properties, such as low tensile and compressive strength, which make it not suitable for bone tissue engineering (BTE). For this reason, HA is often used in combination with different polymers and crosslinkers in the form of composites to improve their mechanical properties and the overall performance of the implantable biomaterials developed for orthopedic applications. This review summarizes recent advances in HA-based biocomposites for bone regeneration, addressing the most widely employed inorganic matrices, the natural and synthetic polymers used as reinforcing components, and the crosslinkers added to improve the mechanical properties of the scaffolds. Besides presenting the main physical and chemical methods in tissue engineering applications, this survey shows that HA biocomposites are generally biocompatible, as per most in vitro and in vivo studies involving animal models and that the results of clinical studies on humans sometimes remain controversial. We believe this review will be helpful as introductory information for scientists studying HA materials in the biomedical field.

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“…Bioactive ceramics (Hydroxyapatite (HA) and bioactive glass might be natural or manufactured. They are chemically comparable to bone and have great compressive strength but low flexibility, offering high rigidity but also fragility [ 49 , 50 ]. Composites are made up of two or more materials with distinct qualities, each with its own set of benefits and drawbacks [ 50 , 51 , 52 ].…”

Section: Properties Of Scaffolds For Periodontal and Bone Regenerationmentioning

confidence: 99%

Locally Applied Repositioned Hormones for Oral Bone and Periodontal Tissue Engineering: A Narrative Review

et al. 2022

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Bone and periodontium are tissues that have a unique capacity to repair from harm. However, replacing or regrowing missing tissues is not always effective, and it becomes more difficult as the defect grows larger. Because of aging and the increased prevalence of debilitating disorders such as diabetes, there is a considerable increase in demand for orthopedic and periodontal surgical operations, and successful techniques for tissue regeneration are still required. Even with significant limitations, such as quantity and the need for a donor area, autogenous bone grafts remain the best solution. Topical administration methods integrate osteoconductive biomaterial and osteoinductive chemicals as hormones as alternative options. This is a promising method for removing the need for autogenous bone transplantation. Furthermore, despite enormous investigation, there is currently no single approach that can reproduce all the physiologic activities of autogenous bone transplants. The localized bioengineering technique uses biomaterials to administer different hormones to capitalize on the host’s regeneration capacity and capability, as well as resemble intrinsic therapy. The current study adds to the comprehension of the principle of hormone redirection and its local administration in both bone and periodontal tissue engineering.

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Nanocomposite of cosubstituted carbonated hydroxyapatite fabricated inside Poly(sodium hyaluronate-acrylamide) hydrogel template prepared by gamma radiation for osteoblast cell regeneration

Cited by 39 publications

References 90 publications

A green composite hydrogel based on xylan and lignin with adjustable mechanical properties, high swelling, excellent UV shielding, and antioxidation properties

A green composite hydrogel based on xylan and lignin with adjustable mechanical properties, high swelling, excellent UV shielding, and antioxidation properties

Recent Advances in Hydroxyapatite-Based Biocomposites for Bone Tissue Regeneration in Orthopedics

Locally Applied Repositioned Hormones for Oral Bone and Periodontal Tissue Engineering: A Narrative Review

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