Nanocomposites in Controlled &amp;amp; Targeted Drug Delivery Systems

Kaurav, Hemlata; Manchanda, Satish; Dua, Kamal; Kapoor, Deepak

doi:10.4028/www.scientific.net/nhc.20.27

Cited by 12 publications

(7 citation statements)

References 115 publications

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“…The inimitable encrusted structure of montmorillonite (clay) enhances the stability of bioactive agents by electrostatic-interaction which helps in controlled delivering by ionexchanging of drug molecules with other ionic interactions facilitated by the biological system [8,60]. Montmorillonite (MMT) clay minerals are mostly reported for the drugdelivering through eye transdermal, colon, and gastro retentive targeted drug delivery.…”

Section: Clay Composites Targeted Drug Delivery Pathwaymentioning

confidence: 99%

“…A number of excipients are available for drug delivery systems, where the use of polymers and polymeric compounds in a conventional pharmaceutical composition as coatings, binders, suspending agents, and surfactants are trending. A composite is a composition that consists of two or more dispersion components having optimized properties as compared to pure materials [8][9][10]. These composites might have micro or nanometric sizes in at least one dimension, so we consider this system as micro or nanocomposite.…”

Section: Introductionmentioning

confidence: 99%

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Micro and Nano Clay-Biopolymer Composites for Drug Delivery

Jabeen¹

2022

Materials Research Foundations

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Clay-based biopolymers are among the most efficient and cost-effective composite materials that find applications in a variety of biomedical applications such as drug delivery. This chapter elaborates the different physical, chemical, and structural properties of clay biopolymeric composites, which makes them most reliable to use for the applications of drug delivery. The main focus of writing this chapter is to explore the composition, structural properties, and route of action of clay-based nanomaterials, along with elaborating the mechanism of the drug delivery system. The synthesis of clay-encapsulated drug formulation and their route of administration has been investigated in this chapter. Data for the synthesis of composites and in vitro study has also been included from the existing literature.

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Section: Clay Composites Targeted Drug Delivery Pathwaymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Micro and Nano Clay-Biopolymer Composites for Drug Delivery

Jabeen¹

2022

Materials Research Foundations

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“…Doxorubicin has been formulated with grapheme oxide and ferrosoferric oxide (GO/Fe 3 O 4 ) conjugated along with lactoferrin for targeting. Methotrexate was delivered to human osteosarcoma cells via Magnesiumaluminum double hydroxide coated on Silicon dioxide nanodots 34 .…”

Section: Targeted Drug Deliverymentioning

confidence: 99%

“…Chitosan has been studied. Nanocomposites have been prepared employing aminopropyl silane along with polyethylene glycol/ polypropylene glycol, magnesium silicate, and locust bean gum respectively for the mentioned drugs 34 .…”

Section: Controlled Drug Deliverymentioning

confidence: 99%

“…The effects of the process parameters on the morphology and on the electrical properties of the nanocomposite films were investigated 59 . 64 , FiltekZ350 XT by 3M (tooth fillers) 65 , chitosan/organic rectorite nanocomposite films (Bactericidal activity), graphene oxide/ Carboxymethylcellulose (targeted drug delivery of anticancer drug doxorubicin) 66 , MD 1 Flex, NANOCLEAN MD 1 and PLACTIVE (Antimicrobial nanocomposites), 67 NovaPro TM (Tooth fillers) 68 . Tremendous progress is evident in science of nanocomposites.…”

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confidence: 99%

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Nanocomposites: - A Recent Overview

Pavan¹,

Madhavi²

2020

GJMR

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Nanocomposites are substances that incorporate nanoparticles (0.5-5% by weight) into a matrix of standard material, which enhances the mechanical strength, toughness including thermal or electrical conductivity and other properties. Nanocomposites are versatile in terms of their applications such as anti-corrosive, healing of bones, sensors, environmental protection, packaging, wastewater treatment, and diagnosis of tumors and other diverse uses. They may be fabricated by blending nanofillers with a polymer to produce a composite. The current trend of processing is by polymerizing monomers. Nanocomposites serve as sustainable solutions to curb global issues. Evaluation is performed on properties such as mechanical, thermal, dispersion, and toxicological. Some marketed products of nanocomposites include In Mat (coating), FiltekZ350 XT by 3M (tooth fillers), chitosan/organic rectorite nanocomposite films (bactericidal activity), graphene oxide/Carboxymethylcellulose (targeted drug delivery of anti-cancer drug doxorubicin), MD1 Flex, Nano Clean MD1, Plactive TM (Antimicrobial nanocomposites) and NovaProTM(Tooth fillers). This article discusses about Nanocomposites–their types, preparation methods, recent research and applications.

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