Nanocomposites of PVA/chitosan blend with BiOCl:Eu3+ prepared by sonochemical route: Forensic and optoelectronics applications

Kalburgi, Bhimanagouda; Prasad, B. Daruka; Lavanya, D.R.; Darshan, G.P.; Gowda, V. C. Veeranna; Hanumantharaju, N.; Venkatesulu, A.; Taj, M Nasreen; Sarma, S C; Nagabhushana, H.

doi:10.1016/j.colsurfa.2022.130446

Cited by 13 publications

(3 citation statements)

References 43 publications

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“…These combinations offer sustained release properties, biocompatibility, biodegradability, non‐toxicity, and robust mechanical strength. Additionally, they possess exceptional spinning ability 23 . For therapeutic purposes, DOX is still preferred as a potential drug for treating breast cancer in chemotherapy and is mainly used in combinational therapies to show maximum effect 24,25 .…”

Section: Discussionmentioning

confidence: 99%

“…Additionally, they possess exceptional spinning ability. 23 For therapeutic purposes, DOX is still preferred as a potential drug for treating breast cancer in chemotherapy and is mainly used in combinational therapies to show maximum effect. 24,25 One literature that supports our finding of using combination therapy with targeted delivery is the SK-OV-3 tumor xenografts that showed enhanced tumor inhibition upon DOX with anti-EGFR immunoviroplexes administration.…”

Section: Discussionmentioning

confidence: 99%

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Development of injectable upconversion nanoparticle‐conjugated doxorubicin theranostics electrospun nanostructure for targeted photochemotherapy in breast cancer

Khan,

Tripathi,

Gandhi

et al. 2024

J Biomedical Materials Res

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Nanotheranostic‐based photochemotherapies with targeted drug delivery have considerably surfaced in cancer therapy. In the presented work, polyethyleneimine‐coated upconversion nanoparticles were engineered to conjugate covalently with doxorubicin. Upconversion nanoparticles (UCNP)‐Doxorubicin (DOX)/synthesized epidermal growth factor receptor‐targeting peptide blended with polymer composite was electrospun and formulated as the injectable dosage form. The size of the UCNP and the nanofiber diameter were assessed as 26.75 ± 1.54 and 162 ± 2.82 nm, respectively. The optimized ratio of dopants resulted in UCNP photoluminescence with maximum emission intensity at around 800 nm upon 980 nm excitation wavelength. The paramagnetic nature of UCNPs and amide conjugation with the drug was confirmed analytically. The loading capacity of UCNP for doxorubicin was determined to be 54.56%, while nanofibers exhibited 98.74% capacity to encapsulate UCNP‐DOX. The release profile of UCNP‐DOX from nanofiber formulation ranged from sustained to controlled, with relative enhancement in acidic conditions. The nanofiber demonstrated good mechanical strength, robust swelling, and degradation rate. Biocompatibility tests showed more than 90% cell viability on L929 and NIH/3T3 cell lines with UCNP‐DOX@NF/pep nanoformulation. The IC50 values of 2.15 ± 0.54, 2.87 ± 0.67, and 3.42 ± 0.45 μg/mL on MDA‐MB‐231, 4T1, and MCF‐7 cancer cell line, respectively, with a significant cellular uptake, has been reported. The UCNP protruded a ≈62.7°C temperature rise within 5 min of 980 nm laser irradiation and a power density of 0.5 W cm−2. The nanoformulation induced reactive oxygen species of 65.67% ± 3.21% and apoptosis by arresting the cell cycle sub‐G1 phase. The evaluation conveys the effectiveness of the developed injectable theranostic delivery system in cancer therapy.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Development of injectable upconversion nanoparticle‐conjugated doxorubicin theranostics electrospun nanostructure for targeted photochemotherapy in breast cancer

Khan,

Tripathi,

Gandhi

et al. 2024

J Biomedical Materials Res

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“…[16] Sonochemical organic synthesis is a technique used for the synthesis of various organic compounds, including drugs, [17][18][19] synthetic chemistry [20][21][22] and polymers. [23] One of the key benefits of sonochemical organic synthesis is the ability to perform reactions under mild reaction conditions, such as; at room temperature and atmospheric pressure. The use of ultrasound waves is critical in increasing the reaction rate and product yield.…”

Section: Introductionmentioning

confidence: 99%

Synthesis of Pyrano[2,3‐d]pyrimidine Derivatives Catalyzed by Trimetallic Multi‐walled Carbon Nanotubes under Ultrasound Irradiation Conditions

Harooni,

Naeimi,

Ghasemi

2023

ChemistrySelect

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This study involves the synthesis of pyrano]2,3‐d[pyrimidine derivatives using the multi‐component reactions (MCRs) under ultrasonic, and nanocatalysis conditions. The reaction efficiency was increased and the reaction time was reduced by using a prepared catalyst accomplished with sonication synergetic effect. Furthermore, the increase in product yield can be due to the synergistic property between metals on the surface of the catalyst. This catalyst was found to be recoverable and highly stable under ultrasonic conditions. The use of trimetallic multi‐walled carbon nanotubes (MWCNTs) proved to be highly effective in synthesis of the pyrano[2,3‐d]pyrimidine derivatives. This is due to their active site, economical catalyst loading, easy workup, reusability, and green reaction conditions. Also, the synthesized products were achieved in excellent yields and short reaction times. Different methods were utilized to characterize the nanocatalyst such as; Fourier‐transform infrared spectroscopy (FT‐IR), X‐ray powder diffraction (XRD), field emission scanning electron microscope (FE‐SEM), energy‐dispersive X‐ray spectroscopy (EDS), thermogravimetric analysis (TGA), and the hot filtration method. The synthesized organic compounds were identified through analyses using the melting point, FT‐IR method, and hydrogen‐1 nuclear magnetic resonance (1H NMR).

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Investigation of lemon peel extract as a natural additive in polyvinyl alcohol/chitosan blend for advanced bioactive food packaging

Fakraoui,

Atanase,

Salhi

et al. 2024

Journal of Polymer Science

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Lemon peel (LP) was integrated into polyvinyl alcohol/chitosan (PVA/CS) to produce innovative active food packaging films via solvent‐casting method. PVA/CS/LP biocomposites were prepared with varying LP contents (1%, 3%, and 5% by weight) to investigate their impact on morphological, thermal, structural, biodegradability, solubility, mechanical, and bioactivity properties of the PVA/CS blend. Scanning electron microscope analysis revealed a uniform dispersion of LP within the matrix. Attenuated total reflectance ‐ fourier transform Infrared spectroscopy (ATR‐FTIR) study confirmed interaction between lemon peel and the matrix. The incorporation of LP enhanced thermal stability and enzymatic activity of PVA/CS films while reducing their UV–vis light transparency. Additionally, the biodegradability of the biocomposites increased, reaching 74% after 30 days of soil burial. Moisture content, water solubility, and swelling decreased with LP content, favoring food preservation. It can be asserted from the tensile test that blending PVA with CS enhances the Young's modulus by 17%. The incorporation of LP into the PVA/CS blend further enhanced the Young's modulus and tensile strength to 1322 and 193 MPa, respectively, attributed to the strong hydrogen bonding between the PVA/CS matrix and LP. Moreover, PVA/CS/LP biocomposites effectively reduced weight loss in cherry tomatoes and inhibited microbial growth, suggesting their potential as eco‐friendly bioactive packaging materials for food preservation.

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Nanocomposites of PVA/chitosan blend with BiOCl:Eu3+ prepared by sonochemical route: Forensic and optoelectronics applications

Cited by 13 publications

References 43 publications

Development of injectable upconversion nanoparticle‐conjugated doxorubicin theranostics electrospun nanostructure for targeted photochemotherapy in breast cancer

Development of injectable upconversion nanoparticle‐conjugated doxorubicin theranostics electrospun nanostructure for targeted photochemotherapy in breast cancer

Synthesis of Pyrano[2,3‐d]pyrimidine Derivatives Catalyzed by Trimetallic Multi‐walled Carbon Nanotubes under Ultrasound Irradiation Conditions

Investigation of lemon peel extract as a natural additive in polyvinyl alcohol/chitosan blend for advanced bioactive food packaging

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