Nanocrystalline Silver (Acticoat) for Itch Relief in the Burns Patient

Brooks, Peter; Phang, Kian Liun; Moazzam, Amber

doi:10.1111/j.1445-2197.2007.04233.x

Cited by 10 publications

(3 citation statements)

References 4 publications

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“…The researchers also reported nanocrystalline silver improved wound healing as well as reduction in PBP (Brooks et al, 2007).…”

Section: Non-pharmacological Interventionsmentioning

confidence: 91%

“…A case study by Brooks, Phang, and Moazzam (2007) demonstrated two weeks of applying nanocrystalline silver to unhealed wound reduced PBP in five cases with different burn associated wound sizes. This intervention was reported to decrease the pruritus from 7.4 to 3.1 of visual analog scale (VAS), which means significant reduction in PBP (Brooks et al, 2007).…”

Section: Non-pharmacological Interventionsmentioning

confidence: 99%

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Development of a Postburn Pruritus Relief Protocol

Kim

2018

Rehabilitation Nursing

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Background: Post burn pruritus is a syndrome of stressful symptoms that is pervasive and occurs in over 90% of burn patients and continues for years after the burn has healed. Post burn pruritus is experienced by burn survivors that may require medical management and effective interventions. Purpose: This article is to show how to relieve post burn pruritus effectively by developing a post burn pruritus relief protocol. Design: A descriptive literature review was conducted and relevant empirical articles written during the year of 2000 to 2014 were appraised to create a post burn pruritus relief protocol. Twenty seven out of 79 articles were selected using pre-established inclusion criteria: any age group experiencing burn related pruritus after second or third degree burns. Data bases were Cochrane Central Register of Controlled Trials, CINAHL, EBSCO, PubMed, the National Guideline Clearinghouse, google scholar, and the American Burn Association web site. Conclusions: This protocol included both non-pharmacological and pharmacological interventions that have been delineated for use and was developed to apply based on the healing stage: pre-healing, healing, and post-healing.

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“…The researchers also reported nanocrystalline silver improved wound healing as well as reduction in PBP (Brooks et al, 2007).…”

Section: Non-pharmacological Interventionsmentioning

confidence: 91%

Section: Non-pharmacological Interventionsmentioning

confidence: 99%

Development of a Postburn Pruritus Relief Protocol

Kim

2018

Rehabilitation Nursing

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“…Hence, a combination of interventions is needed to achieve satisfactory relief in the majority of patients. [2,38] We advocate the judicious and stepwise use of agents in [33] / antihistamines Brooks et al [35] / acticoat Allison et al [36] Eldardiri et al [37] / antihistamines and gabapentin…”

Section: Additional Remarks Polytherapy For Postburn Itchmentioning

confidence: 99%

Review of therapeutic agents for burns pruritus and protocols for management in adult and paediatric patients using the GRADE classification

Goutos

Clarke

Upson

et al. 2010

Indian J Plast Surg

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To review the current evidence on therapeutic agents for burns pruritus and use the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) classification to propose therapeutic protocols for adult and paediatric patients. All published interventions for burns pruritus were analysed by a multidisciplinary panel of burns specialists following the GRADE classification to rate individual agents. Following the collation of results and panel discussion, consensus protocols are presented. Twenty-three studies appraising therapeutic agents in the burns literature were identified. The majority of these studies (16 out of 23) are of an observational nature, making an evidence-based approach to defining optimal therapy not feasible. Our multidisciplinary approach employing the GRADE classification recommends the use of antihistamines (cetirizine and cimetidine) and gabapentin as the first-line pharmacological agents for both adult and paediatric patients. Ondansetron and loratadine are the second-line medications in our protocols. We additionally recommend a variety of non-pharmacological adjuncts for the perusal of clinicians in order to maximise symptomatic relief in patients troubled with postburn itch. Most studies in the subject area lack sufficient statistical power to dictate a ‘gold standard’ treatment agent for burns itch. We encourage clinicians to employ the GRADE system in order to delineate the most appropriate therapeutic approach for burns pruritus until further research elucidates the most efficacious interventions. This widely adopted classification empowers burns clinicians to tailor therapeutic regimens according to current evidence, patient values, risks and resource considerations in different medical environments.

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