Nanoemulsion of Lavandula angustifolia Essential Oil/Gold Nanoparticles: Antibacterial Effect against Multidrug-Resistant Wound-Causing Bacteria

Fadel, Balqis A.; Elwakil, Bassma H.; Fawzy, Esraa E.; Shaaban, Marwa M.; Olama, Zakia A.

doi:10.3390/molecules28196988

Cited by 8 publications

(4 citation statements)

References 53 publications

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“…Of course, in this study examined the impact of LEO-NE for the first time on P. aeruginosa , which indicates its antimicrobial effects. In line with this study, Fadel et al (2023) examined the antibacterial properties of LEO-NE on Proteus mirabilis ( 28 ). The study conducted by Derya Demir et al in 2023 demonstrated the efficacy of lavandula in enhancing wound healing in individuals with diabetes.…”

Section: Discussionmentioning

confidence: 53%

Effect of collagen hydrogel containing Lavandula officinalis essential oil nanoemulsion in wound healing of infectious burn

Teymouri,

Mohammadimehr,

Ahanjan

et al. 2024

IJM

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Background and Objectives: The main cause of mortality in burn patients is infection from burns. Drug-resistant bacteria are the main causes of wound infection, so alternative antibiotic therapies hold significant importance. The objective of this study was to examine the impact of a collagen hydrogel that contains a nanoemulsion of Lavandula essential oil on the heal- ing process of infected burn wounds. Materials and Methods: In this experimental study, 20 rats were randomly divided after applying burns with a 10 mm diameter hot plate and infecting the wounds with multidrug-resistant Pseudomonas aeruginosa into four groups, including a positive control, a negative control, the first experiment (collagen hydrogel), and the second experiment (collagen hydrogel containing Lavandula essential oil nanoemulsion). On the 4th, 11th, and 18th days, tissue samples were taken for pathology studies. The important parameters in burn wound healing with hematoxylin and eosin and Masson's trichrome staining meth- ods were investigated and scored according to Abramov’s method. Results: Based on the pathology findings, experimental groups 1 and 2 compared to the negative and positive control groups were effective in rat infection wound healing. The hydrogel scaffold in the experimental groups increased fibroblasts and an- giogenesis compared to the control groups. Epithelization was noticed only in the hydrogel group containing nanoemulsion. Conclusion: The study findings suggest that the use of collagen hydrogel with Lavandula essential oil nanoemulsion has potential as a wound dressing. This is because it has the potential to effectively promote healing and act as an antibacterial agent to prevent infections.

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Section: Discussionmentioning

confidence: 53%

Effect of collagen hydrogel containing Lavandula officinalis essential oil nanoemulsion in wound healing of infectious burn

Teymouri,

Mohammadimehr,

Ahanjan

et al. 2024

IJM

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“…L-EO is derived from the blossoms of Lavandula angustifolia [252]. As described in Section 2.13, the major components of L-EO are linalool and linalyl acetate [107].…”

Section: Lavender-essential Oil (L-eo)mentioning

confidence: 99%

Multiplicative Effects of Essential Oils and Other Active Components on Skin Tissue and Skin Cancers

Kim,

Hong

2024

IJMS

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Naturally derived essential oils and their active components are known to possess various properties, ranging from anti-oxidant, anti-inflammatory, anti-bacterial, anti-fungal, and anti-cancer activities. Numerous types of essential oils and active components have been discovered, and their permissive roles have been addressed in various fields. In this comprehensive review, we focused on the roles of essential oils and active components in skin diseases and cancers as discovered over the past three decades. In particular, we opted to highlight the effectiveness of essential oils and their active components in developing strategies against various skin diseases and skin cancers and to describe the effects of the identified essential-oil-derived major components from physiological and pathological perspectives. Overall, this review provides a basis for the development of novel therapies for skin diseases and cancers, especially melanoma.

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“…The recently produced formulation of nano-gold and nano-Lavandula angustifolia demonstrated complete eradication of pre-existing P. mirabilis biofilm. The MIC and minimum biofilm eradication concentration (MBEC) values for this formulation were determined to be 8 and 16 g/mL, respectively (Figure 2) (Fadel et al, 2023).…”

Section: Application Of Microemulsion Essential Oilmentioning

confidence: 99%

Microemulsion technology: Nanoparticle-based emulsion as a sustainable natural product formulation

Sembiring,

Arsyadi,

Riadi

2024

Pharm Educ

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Natural products refer to chemicals or compounds from living creatures occurring naturally in the environment. Natural commodities, such as spices, herbs, and medical remedies, are often used as additions. Natural products have many advantages, such as their environmentally sustainable nature, compatibility with the skin, affordability, and widespread availability. Nevertheless, developing natural products has several challenges, such as limited options for ingredients, functional limitations of natural substances, considerations about stability and preservation, consumer perceptions and expectations, and the variability in the composition of natural products. Microemulsions are prevalent emulsions that incorporate nanoparticles. A microemulsion is a homogeneous, transparent liquid consisting of oil, water, and a surfactant, often combined with a cosurfactant. The use of microemulsions has been extensively observed in many chemical and pharmacological applications owing to their unique attributes, such as a significant interfacial area, little interfacial tension, and the ability to solubilise and deliver hydrophobic substances. Therefore, the present review paper aims to comprehensively analyse microemulsion technology and its applications as an environmentally friendly formulation for natural products. Here, we propose strategies and research on microemulsions to overcome problems in natural product formulations.

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Nanoemulsion of Lavandula angustifolia Essential Oil/Gold Nanoparticles: Antibacterial Effect against Multidrug-Resistant Wound-Causing Bacteria

Cited by 8 publications

References 53 publications

Effect of collagen hydrogel containing Lavandula officinalis essential oil nanoemulsion in wound healing of infectious burn

Effect of collagen hydrogel containing Lavandula officinalis essential oil nanoemulsion in wound healing of infectious burn

Multiplicative Effects of Essential Oils and Other Active Components on Skin Tissue and Skin Cancers

Microemulsion technology: Nanoparticle-based emulsion as a sustainable natural product formulation

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