Nanoencapsulated Systems for Delivery of Phytopharmaceuticals

Renovato‐Núñez, Jacqueline; Cobos‐Puc, Luis Enrique; Viveros‐Valdez, Ezequiel; Iliná, Anna; Segura‐Ceniceros, Elda Patricia; Rodríguez‐Herrera, Raúl; Silva‐Belmares, Sonia Yesenia

doi:10.1002/9781394167708.ch7

Cited by 2 publications

(2 citation statements)

References 100 publications

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“…These nanoparticles, such as nanocapsules and nanoemulsions, have been developed for specific active substances to increase the release and stability of the encapsulated compounds. 32 Nanoemulsions are classified as two-phase liquid systems, characterized by droplet sizes below 200 nm, thereby offering augmented stability and the potential for scale-up. 33 Techniques for liquid-based nanoencapsulation encompass coacervation, inclusion encapsulation, nanoprecipitation, emulsification-solvent evaporation, and supercritical fluid methods.…”

Section: Nanoencapsulationmentioning

confidence: 99%

“…Liquid–liquid nanoencapsulated systems involve encapsulating liquid bioactive compounds in nanoparticles that are liquid-based (such as oil and water). These nanoparticles, such as nanocapsules and nanoemulsions, have been developed for specific active substances to increase the release and stability of the encapsulated compounds . Nanoemulsions are classified as two-phase liquid systems, characterized by droplet sizes below 200 nm, thereby offering augmented stability and the potential for scale-up .…”

Section: Nanoencapsulationmentioning

confidence: 99%

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Saffron Nanoencapsulation (Crocus sativus) and Its Role in Food Science: Types and Techniques

Borjizadeh,

Ahari,

Özdal

et al. 2024

ACS Food Sci. Technol.

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The encapsulation of saffron holds great importance as it contributes to the improvement of its stability, purity, and targeted release of its bioactive components. The purpose of this review is to provide comprehensive information about the main methods for saffron encapsulation, types of encapsulation, and the current status of its patents in the field of food science. Numerous studies have been conducted to encapsulate saffron and its ingredients within micro/nanoparticles. According to them, nanoliposomes, polymeric nanoparticles, nanodroplets, and nanofibers have been employed for saffron encapsulation. These nanocarriers were synthesized using ultrasonication, emulsification, spray drying, freeze-drying, electrospinning, chemical synthesis, and ionic gelation. The size, stability, bioavailability, and release kinetics were crucial for their specific application. In general, ionic gelation, ultrasonication, and spray drying were the most popular methods for saffron encapsulation, respectively. Only a limited number of patents exist about nanosaffron for food science applications.

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Section: Nanoencapsulationmentioning

confidence: 99%

Section: Nanoencapsulationmentioning

confidence: 99%

Saffron Nanoencapsulation (Crocus sativus) and Its Role in Food Science: Types and Techniques

Borjizadeh,

Ahari,

Özdal

et al. 2024

ACS Food Sci. Technol.

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Lipids Fortified Nano Phytopharmaceuticals: A Breakthrough Approach in Delivering Bio-actives for Improved Therapeutic Efficacy

Shah,

Chauhan,

Madhu

et al. 2025

PNT

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Phytopharmaceuticals, derived from natural sources, manifest tremendous potential for therapeutic applications. Nevertheless, effective delivery of these bio-actives presents significant challenges. A breakthrough in fortifying phytopharmaceuticals within phosphatidylcholine is a promising remedy to overcome solubility, permeability, and other related drawbacks. This intrinsic lipid, which is obtained from both natural and synthetic sources, confers numerous benefits, encompassing heightened solubility, augmented bioavailability, and enhanced stability. The conjugation of phytopharmaceuticals with phosphatidylcholine enables improved dermal permeation, absorption, targeted distribution, and the possibility of synergistic results, eventually improving therapeutic efficacy. Additionally, the use of phytopharmaceuticals enriched with phosphatidylcholine presents a promising route for overcoming the limitations imposed by conventional delivery techniques, encouraging more effective treatments. The review provides a thorough analysis of phosphatidylcholine- incorporated phytopharmaceuticals as nanomedicine with variables that significantly affect their therapeutic efficacy. Moreover, the review elaborates on how phosphatidylcholine improves solubility, permeability, and tissue distribution and boosts the potential of phytopharmaceuticals. Further, the review underscores the significance of nano-formulation strategies, analytical methodologies, and forthcoming prospects to propel this field forward. Furthermore, the review emphasizes the potential inherent in this innovative approach while highlighting the importance of additional research endeavors and collaborative initiatives to unlock the therapeutic benefits of phosphatidylcholinefortified phytopharmaceuticals, enhancing patient well-being.

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Nanoencapsulated Systems for Delivery of Phytopharmaceuticals

Cited by 2 publications

References 100 publications

Saffron Nanoencapsulation (Crocus sativus) and Its Role in Food Science: Types and Techniques

Saffron Nanoencapsulation (Crocus sativus) and Its Role in Food Science: Types and Techniques

Lipids Fortified Nano Phytopharmaceuticals: A Breakthrough Approach in Delivering Bio-actives for Improved Therapeutic Efficacy

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