Nanoencapsulation and bioaccessibility of polyphenols of aqueous extracts from Bauhinia forficata link

Souza, Bárbara Verônica Cardoso de; Sousa, Mariana de Morais; Sattler, J.; Santana, Ana Cristina Sousa Gramoza Vilarinho; Carvalho, Rusbene Bruno Fonseca de; Neto, José de Sousa Lima; Borges, Fernando de Matos; Numa, Iramaia Angélica Neri; Ribeiro, Alessandra Braga; Nunes, Lívio César Cunha

doi:10.1016/j.fochms.2022.100144

Cited by 7 publications

(10 citation statements)

References 97 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These results were expected due to the small quantity of raw material employed when compared to the spray dryer scale. Furthermore, some losses occur throughout the equipment [ 31 , 32 ], mainly due to the powder adhesion to the equipment walls as well as to the cyclone low efficiency to separate small particles, with their possible aspiration by the vacuum system [ 31 , 33 ]. The same phenomenon has been verified by other authors.…”

Section: Resultsmentioning

confidence: 99%

“…Concerning the loading capacity, the kaempferol-3- O -(acetyl-rhamnoside)-hexoside showed the highest value (0.00320%), followed by 4- O -caffeoylquinic acid (0.00225%) and 1- O -caffeoylquinic acid (0.00205%). These parameters are crucial to evaluate the encapsulation efficiency that expresses the amount of extract entrapped in microparticles [ 32 , 36 ]. Many conditions such as compounds solubility in the encapsulating agent or in the aqueous phase, aggregation or precipitation of molecules, or even spray-drying conditions (e.g., flow rate, inlet, and outlet temperature) can affect the encapsulation efficiency [ 36 , 37 , 38 ].…”

Section: Resultsmentioning

confidence: 99%

“…The loaded microparticles demonstrated a slightly higher viscosity than the empty ones, which may be related to the high moisture content. On the other hand, the presence of larger microparticles, which increase the flow resistance, as well as the influence of the molecular weights of the bioactive compounds present inside, may contribute to the loaded microparticles’ increased viscosity observed [ 32 ]. This parameter is also correlated with the production yield, since microparticles with higher viscosities tend to have lower yields as the droplets formed are stickier and easily retained in the spray dryer [ 31 , 32 ].…”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Development and Characterization of Microparticles with Actinidia arguta Leaves Extract by Spray-Drying: A New Mind-Set Regarding Healthy Compounds for Oral Mucositis

et al. 2023

View full text Add to dashboard Cite

Actinidia arguta leaves have gained notoriety over the past years due to their rich bioactive composition with human pro-healthy effects, particularly in relation to antioxidants. Nevertheless, antioxidants are well known for their chemical instability, making it necessary to develop suitable delivery systems, such as microparticles, to provide protection and ensure a controlled release. The aim of this work was to produce polymeric particles of A. arguta leaves extract by spray-drying that may improve the oral mucositis condition. Microparticles were characterized by size, shape, antioxidant/antiradical activities, swelling capacity, moisture content, and effect on oral cells (TR146 and HSC-3) viability, with the aim to assess their potential application in this oral condition. The results attested the microparticles’ spherical morphology and production yields of 41.43% and 36.40%, respectively, for empty and A. arguta leaves extract microparticles. The A. arguta leaves extract microparticles obtained the highest phenolic content (19.29 mg GAE/g) and antioxidant/antiradical activities (FRAP = 81.72 µmol FSE/g; DPPH = 4.90 mg TE/g), being perceived as an increase in moisture content and swelling capacity. No differences were observed between empty and loaded microparticles through FTIR analysis. Furthermore, the exposure to HSC-3 and TR146 did not lead to a viability decrease, attesting their safety for oral administration. Overall, these results highlight the significant potential of A. arguta leaves extract microparticles for applications in the pharmaceutical and nutraceutical industries.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Development and Characterization of Microparticles with Actinidia arguta Leaves Extract by Spray-Drying: A New Mind-Set Regarding Healthy Compounds for Oral Mucositis

et al. 2023

View full text Add to dashboard Cite

show abstract

“…This process enhances their stability. This makes them suitable for inclusion in a range of nutraceutical formulations . To provide prolonged and targeted administration, the encapsulating technique also permits the regulated release of herbal actives .…”

Section: Nanoencapsulationmentioning

confidence: 99%

Saffron Nanoencapsulation (Crocus sativus) and Its Role in Food Science: Types and Techniques

Borjizadeh,

Ahari,

Özdal

et al. 2024

ACS Food Sci. Technol.

View full text Add to dashboard Cite

The encapsulation of saffron holds great importance as it contributes to the improvement of its stability, purity, and targeted release of its bioactive components. The purpose of this review is to provide comprehensive information about the main methods for saffron encapsulation, types of encapsulation, and the current status of its patents in the field of food science. Numerous studies have been conducted to encapsulate saffron and its ingredients within micro/nanoparticles. According to them, nanoliposomes, polymeric nanoparticles, nanodroplets, and nanofibers have been employed for saffron encapsulation. These nanocarriers were synthesized using ultrasonication, emulsification, spray drying, freeze-drying, electrospinning, chemical synthesis, and ionic gelation. The size, stability, bioavailability, and release kinetics were crucial for their specific application. In general, ionic gelation, ultrasonication, and spray drying were the most popular methods for saffron encapsulation, respectively. Only a limited number of patents exist about nanosaffron for food science applications.

show abstract

“…There are a multitude of techniques to obtain fine particles from extracts such as spraydrying or freeze-drying that are well documented in the literature [23][24][25]. More novel techniques, such as those involving the use of supercritical fluids (SCFs), remain to be more deeply investigated.…”

Section: Introductionmentioning

confidence: 99%

Generation of Highly Antioxidant Submicron Particles from Myrtus communis Leaf Extract by Supercritical Antisolvent Extraction Process

et al. 2023

View full text Add to dashboard Cite

Submicron particles have been produced from an ethanolic extract of Myrtus communnis leaves using supercritical carbon dioxide technology, hereinafter referred to as Supercritical Antisolvent Extraction (SAE). The influence of pressure (9–20 MPa), temperature (308 and 328 K) and injection rate (3 and 8 mL/min) on the particles’ precipitation has been investigated, and it has been confirmed that increases in pressure and temperature led to smaller particle sizes. The obtained particles had a quasi-spherical shape with sizes ranging from 0.42 to 1.32 μm. Moreover, the bioactivity of the generated particles was assessed and large contents of phenolic compounds with a high antioxidant activity were measured. The particles were also subjected to in vitro studies against oxidative stress. The myrtle particles demonstrated cytoprotective properties when applied at low concentrations (1 μM) to macrophage cell lines.

show abstract

Nanoencapsulation and bioaccessibility of polyphenols of aqueous extracts from Bauhinia forficata link

Cited by 7 publications

References 97 publications

Development and Characterization of Microparticles with Actinidia arguta Leaves Extract by Spray-Drying: A New Mind-Set Regarding Healthy Compounds for Oral Mucositis

Development and Characterization of Microparticles with Actinidia arguta Leaves Extract by Spray-Drying: A New Mind-Set Regarding Healthy Compounds for Oral Mucositis

Saffron Nanoencapsulation (Crocus sativus) and Its Role in Food Science: Types and Techniques

Generation of Highly Antioxidant Submicron Particles from Myrtus communis Leaf Extract by Supercritical Antisolvent Extraction Process

Contact Info

Product

Resources

About