This investigation aims to study Hall's current effect on the peristaltic flow of a Jeffrey nanofluid with variable thermal conductivity in an inclined asymmetric channel. Joule heating and oblique magnetic field effects are taken into consideration. A system of ordinary differential equations is obtained under the approximation of low Reynolds number and long wavelength, which consists of momentum, energy, and concentration equations. The influences of penitent physical parameters on the distribution of velocity, temperature, and concentration have been discussed graphically. Streamline graphs are offered in the terminus, which elucidates the trapping bolus phenomenon. The resulting equations are solved numerically using the ND Solver technique. The thermal conductivity parameter causes the pressure gradient to increase while reducing the pressure rise. Our present model can be applied to physiological flow transportation in the veins with heat transfer. K E Y W O R D S Hall current, Jeffrey nanofluid, ND Solver, peristaltic flow, variable thermal conductivity