Nanoformulated herbal bioactives for the treatment of neurodegenerative disorders

Sajadimajd, Soraya; Moradi, Seyed Zachariah; Akbari, Vali; Aghaz, Faranak; Farzaei, Mohammad Hosein

doi:10.1016/b978-0-12-824385-5.00008-x

Cited by 5 publications

(2 citation statements)

References 138 publications

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“…Therefore, traditional herbal medicine can be expressed as the use of plants or herbs as remedies in medicine in the following forms of herbal materials, herbs, herbal preparations, and finished herbal products containing active ingredients derived from plants/plant materials, according to the definition of the WHO [94]. Nano-formulated herbal bioactive could be applied for treating many human diseases such as neurodegenerative diseases, which can be nano-formulated using curcumin, quercetin, resveratrol, rutin, piperine, gallic acid, ferulic acid, and selenium [95]. There are many systems for delivering herbal bioactivebased nano-drugs, such as liposomes, nanoemulsions, niosomes, phytosome, polymeric micelles, nanoparticles, nanogels/hydrogel, and other novel drug delivery systems herbal formulations [87].…”

Section: Phytomedicine and Human Healthmentioning

confidence: 99%

A Comparative Photographic Review on Higher Plants and Macro-Fungi: A Soil Restoration for Sustainable Production of Food and Energy

et al. 2022

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The Kingdom of Plantae is considered the main source of human food, and includes several edible and medicinal plants, whereas mushrooms belong to the Kingdom of fungi. There are a lot of similar characteristics between mushrooms and higher plants, but there are also many differences among them, especially from the human health point of view. The absences of both chlorophyll content and the ability to form their own food are the main differences between mushrooms and higher plants. The main similar attributes found in both mushrooms and higher plants are represented in their nutritional and medicinal activities. The findings of this review have a number of practical implications. A lot of applications in different fields could be found also for both mushrooms and higher plants, especially in the bioenergy, biorefinery, soil restoration, and pharmaceutical fields, but this study is the first report on a comparative photographic review between them. An implication of the most important findings in this review is that both mushrooms and plants should be taken into account when integrated food and energy are needed. These findings will be of broad use to the scientific and biomedical communities. Further investigation and experimentation into the integration and production of food crops and mushrooms are strongly recommended under different environmental conditions, particularly climate change.

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Section: Phytomedicine and Human Healthmentioning

confidence: 99%

A Comparative Photographic Review on Higher Plants and Macro-Fungi: A Soil Restoration for Sustainable Production of Food and Energy

et al. 2022

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“…Nature is one of the main sources of active therapeutic agents, chemical compounds, and drugs with a wide variety of pharmacological effects, including antitumor, cardioprotective, antiviral, neuroprotective, anti-inflammatory, and antibacterial activities [ 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 ]. In recent decades, various mitochondrial-targeted components with significant anticarcinoma potential have been identified and obtained from natural compounds.…”

Section: Synthetic Agents and Candidate Phytocompounds In Modulation ...mentioning

confidence: 99%

Marine Compounds, Mitochondria, and Malignancy: A Therapeutic Nexus

et al. 2022

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The marine environment is important yet generally underexplored. It contains new sources of functional constituents that can affect various pathways in food processing, storage, and fortification. Bioactive secondary metabolites produced by marine microorganisms may have significant potential applications for humans. Various components isolated from disparate marine microorganisms, including fungi, microalgae, bacteria, and myxomycetes, showed considerable biological effects, such as anticancer, antioxidant, antiviral, antibacterial, and neuroprotective activities. Growing studies are revealing that potential anticancer effects of marine agents could be achieved through the modulation of several organelles. Mitochondria are known organelles that influence growth, differentiation, and death of cells via influencing the biosynthetic, bioenergetic, and various signaling pathways related to oxidative stress and cellular metabolism. Consequently, mitochondria play an essential role in tumorigenesis and cancer treatments by adapting to alterations in environmental and cellular conditions. The growing interest in marine-derived anticancer agents, combined with the development and progression of novel technology in the extraction and cultures of marine life, led to revelations of new compounds with meaningful pharmacological applications. This is the first critical review on marine-derived anticancer agents that have the potential for targeting mitochondrial function during tumorigenesis. This study aims to provide promising strategies in cancer prevention and treatment.

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Modulation of hypoxia-inducible factor-1 signaling pathways in cancer angiogenesis, invasion, and metastasis by natural compounds: a comprehensive and critical review

Fakhri,

Moradi,

Faraji

et al. 2023

Cancer Metastasis Rev

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Nanoformulated herbal bioactives for the treatment of neurodegenerative disorders

Cited by 5 publications

References 138 publications

A Comparative Photographic Review on Higher Plants and Macro-Fungi: A Soil Restoration for Sustainable Production of Food and Energy

A Comparative Photographic Review on Higher Plants and Macro-Fungi: A Soil Restoration for Sustainable Production of Food and Energy

Marine Compounds, Mitochondria, and Malignancy: A Therapeutic Nexus

Modulation of hypoxia-inducible factor-1 signaling pathways in cancer angiogenesis, invasion, and metastasis by natural compounds: a comprehensive and critical review

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