“…10,11 These properties enable the fabrication of nanocarriers that can respond to various stimuli, such as ionic strength, pH, and temperature. 12,13 The high capacity for absorbing large amounts of water or biological fluids, while retaining their structure, is due to the presence of polar and hydrophilic groups in the polymeric structure, such as -OH, -CONH-, -CONH 2 , and -SO 3 H. 14,15 Studies reported in the literature have demonstrated that nanogels can reduce the premature release of bioactive molecules a Universidade de Franca, Av. Dr Armando Salles Oliveira 201, Franca, SP, 14404-600, Brazil.…”