Nanomaterial-based electroanalytical sensors for the selected prohibited anabolic agents, hormones and metabolic modulators and their sensitive assays

Kaya, S. Irem; Yıldırım, Sercan; Çetinkaya, Ahmet; Erkmen, Cem; Uslu, Bengi

doi:10.1016/j.trac.2021.116457

Cited by 10 publications

(4 citation statements)

References 83 publications

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“…Hormones are key messengers that convey essential information in living organisms and are used to regulate physiological processes [ 178 ]. Among them are estrogens, a group of chemically similar steroid hormones found in animals and humans.…”

Section: Application Of Silver Nanoparticles In Voltammetric and Ampe...mentioning

confidence: 99%

The Role of Silver Nanoparticles in Electrochemical Sensors for Aquatic Environmental Analysis

Ivanišević

2023

Sensors

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With rapidly increasing environmental pollution, there is an urgent need for the development of fast, low-cost, and effective sensing devices for the detection of various organic and inorganic substances. Silver nanoparticles (AgNPs) are well known for their superior optoelectronic and physicochemical properties, and have, therefore, attracted a great deal of interest in the sensor arena. The introduction of AgNPs onto the surface of two-dimensional (2D) structures, incorporation into conductive polymers, or within three-dimensional (3D) nanohybrid architectures is a common strategy to fabricate novel platforms with improved chemical and physical properties for analyte sensing. In the first section of this review, the main wet chemical reduction approaches for the successful synthesis of functional AgNPs for electrochemical sensing applications are discussed. Then, a brief section on the sensing principles of voltammetric and amperometric sensors is given. The current utilization of silver nanoparticles and silver-based composite nanomaterials for the fabrication of voltammetric and amperometric sensors as novel platforms for the detection of environmental pollutants in water matrices is summarized. Finally, the current challenges and future directions for the nanosilver-based electrochemical sensing of environmental pollutants are outlined.

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Section: Application Of Silver Nanoparticles In Voltammetric and Ampe...mentioning

confidence: 99%

The Role of Silver Nanoparticles in Electrochemical Sensors for Aquatic Environmental Analysis

Ivanišević

2023

Sensors

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“…Nanomaterials have dimensions from 1 to 100 nm, and their properties are different from the properties of molecules and crystalline solids on a larger scale. Carbon-based nanomaterials, such as carbon nanotubes, graphene, and carbon black, show advantageous characteristics, such as a high specific surface area, and excellent electrical conductivity [80].…”

Section: Nanomaterial-modified Electrochemical Aptasensorsmentioning

confidence: 99%

Relevant Aspects in the Development of Electrochemical Aptasensors for the Determination of Antibiotics—A Review

da Silva,

Pereira

2023

Electrochem

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Aptamers are three-dimensional structures of DNA or RNA that present high affinity and selectivity to specific targets, obtained through in vitro screening. Aptamers are used as biological recognizers in electrochemical biosensors, the so-called aptasensors, providing greater specificity in recognizing the most diverse analytes. Electrochemical aptasensors have extremely relevant characteristics, such as high sensitivity, low cost compared to other biorecognizers such as antibodies, and excellent compatibility, being considered one of the most promising alternative methods in several areas, such as biomedical diagnosis and monitoring environmental contaminants. In this sense, the present work reviews the relevant aspects of methodologies based on electrochemical aptasensors and their applications in determining antibiotics, seeking to foster innovation in electrochemical biosensors.

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“…12 Therefore, the World Health Organization (WHO) and the World Anti-Doping Agency (WADA) have prohibited CLB abuse in drug syntheses and animal husbandry. 13,14 Abominably, unethical merchants privately applied CLB as an illegal additive in feeds to make exorbitant profits. 15 Therefore, it is urgent and meaningful to quantitatively detect CLB for food safety and human health.…”

Section: ■ Introductionmentioning

confidence: 99%

“… In clinical medicine, CLB is primitively employed as a drug for the treatment of respiratory diseases at appropriate medical doses, including bronchial asthma, chronic bronchitis, and emphysema. , In stock farming, CLB is usually known as “leptin” or “lean meat powder,” which can promote animal growth, protein accretion, lean meat percentage increase, and fatty acid degradation as well as lipolysis. − However, CLB residues can often accumulate in muscles and viscera of animal or human bodies through the food chain and degrade difficultly due to its long half-life and slow metabolism. , Then, a series of toxic side effects on human health were caused, including dizziness, nausea, palpitation, nervousness, muscular tremors, shivering, and even inducing tumors. , Actually, as early as 1990, food poisoning incidents were reported arising from the consumption of CLB-contaminated meats . Therefore, the World Health Organization (WHO) and the World Anti-Doping Agency (WADA) have prohibited CLB abuse in drug syntheses and animal husbandry. , Abominably, unethical merchants privately applied CLB as an illegal additive in feeds to make exorbitant profits . Therefore, it is urgent and meaningful to quantitatively detect CLB for food safety and human health.…”

Section: Introductionmentioning

confidence: 99%

Ultrasensitive Eu-Based MOF Luminescence Sensor for Clenbuterol Visible Recognition

Zhang,

Ding,

Jiao

et al. 2024

Inorg. Chem.

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Clenbuterol (CLB) as an illegal feed additive may cause a great security risk to food safety. However, convenient and efficient detection means for CLB in practical application remain a formidable challenge. Herein, a stable Eu-based organic framework {[H2N(CH3)2]2[Eu2(ttca)2]·H2O}n (compound 1) (H4ttca = [1,1′:2′,1″-terphenyl]-4,4′,4″,5′-tetracarboxylic acid) has been harvested, exhibiting excellent chemical stability and thermal stability. Luminescence investigation reveals that compound 1 can sensitively and selectively detect CLB without being affected by different components from simulated serum and urine (limit detection: 22.7 nM). Furthermore, sensor 1 can also be applicable to CLB recognition in real swine feeds, presenting excellent anti-interference performance. The good cyclicity of compound 1 endows CLB determination with many advantages: low cost, high stability, and simplicity. Importantly, in view of the indication of the luminescence color (red to blue), test membranes were fabricated and employed for convenient and fast CLB detection, providing a valuable scheme for the visual monitoring of CLB in meat products. This work enriches rare earth metal compounds and luminescence sensor portfolios and breaks the concentration record (nM) for detecting CLB compared with reported complex materials, providing an effective monitoring platform for CLB visually.

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Nanomaterial-based electroanalytical sensors for the selected prohibited anabolic agents, hormones and metabolic modulators and their sensitive assays

Cited by 10 publications

References 83 publications

The Role of Silver Nanoparticles in Electrochemical Sensors for Aquatic Environmental Analysis

The Role of Silver Nanoparticles in Electrochemical Sensors for Aquatic Environmental Analysis

Relevant Aspects in the Development of Electrochemical Aptasensors for the Determination of Antibiotics—A Review

Ultrasensitive Eu-Based MOF Luminescence Sensor for Clenbuterol Visible Recognition

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