Nanomaterials and Scaffolds for Tissue Engineering and Regenerative Medicine

Kargozar, Saeid; Nazarnezhad, Simin; Kermani, Farzad; Baino, Francesco

doi:10.1002/9781119558026.ch11

Cited by 3 publications

(1 citation statement)

References 183 publications

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“…Hence, the current aim is designing and building multifunctional nanosystems (polymeric materials) for diagnosis and therapeutics [10]. Even though abundant theragnostic materials, both organic and inorganic, in the form of scaffolds, nanoparticles, hydrogels, colloids, microspheres, etc., have been engineered and investigated for cancer treatment, all the said criteria do not fit into a single system [11][12][13]. Most of the design processes used to develop a particular theragnostic nanomaterial are by: (a) a combination/binding of target drugs/stimulants to nanomaterial; (b) a merger with an image contrast enhancer; (c) the effective incorporation of two or more therapeutic imaging agents in one nanomaterial [14].…”

Section: Introductionmentioning

confidence: 99%

Polymeric Theragnostic Nanoplatforms for Bone Tissue Engineering

Banerjee

Madhyastha

2023

JNT

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Nanomaterial-based tissue engineering strategies are precisely designed and tweaked to contest specific patient needs and their end applications. Though theragnostic is a radical term very eminent in cancer prognosis, of late, theragnostic approaches have been explored in the fields of tissue remodulation and reparation. The engineering of theragnostic nanomaterials has opened up avenues for disease diagnosis, imaging, and therapeutic treatments. The instantaneous monitoring of therapeutic strategy is expected to co-deliver imaging and pharmaceutical agents at the same time, and nanoscale carrier moieties are convenient and efficient platforms in theragnostic applications, especially in soft and hard tissue regeneration. Furthermore, imaging modalities have extensively contributed to the signal-to-noise ratio. Simultaneously, there is an accumulation of high concentrations of therapeutic mediators at the defect site. Given the confines of contemporary bone diagnostic systems, the clinical rationale demands nano/biomaterials that can localize to bone-diseased sites to enhance the precision and prognostic value for osteoporosis, non-healing fractures, and/or infections, etc. Furthermore, bone theragnostics may have an even greater clinical impact and multimodal imaging procedures can overcome the restrictions of individual modalities. The present review introduces representative theragnostic polymeric nanomaterials and their advantages and disadvantages in practical use as well as their unique properties.

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Section: Introductionmentioning

confidence: 99%

Polymeric Theragnostic Nanoplatforms for Bone Tissue Engineering

Banerjee

Madhyastha

2023

JNT

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Nanomaterials for Biomedical Applications

Wirtu,

Jule,

Nagaraj

2024

Advances in Chemical and Materials Engineering

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In this chapter, the authors present nanomaterials for biomedical application as promising technology of drug delivery, biosensors, and tissue engineering. Nanomaterials have revolutionized the field of biomedical applications because they provide sophisticated solutions for tissue engineering, biosensing, and drug administration through treating and diagnosing a variety of human ailments, including cancer, heart disease, dental conditions, and disorders of the central and peripheral nervous systems. Nanomaterials play a crucial role in achieving sustainable development goals by offering innovative solutions across various health sectors. In this chapter, the author discussion attempts to indicate the revolutionary impact of nanomaterials on biomedical research and clinical practice through an extensive discussion of recent developments and problems in the areas of nanomaterials for biomedical applications: drug delivery, biosensors, and tissue engineering.

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Synergistic Effects of Nanomaterials in Drug Delivery, Biosensing, and Tissue Engineering

Parthasarathy,

Das,

Patnaik

et al. 2024

Advances in Chemical and Materials Engineering

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The use of nanomaterials in biomedical applications has revolutionized drug delivery, biosensing, and tissue engineering. These materials offer improved bioavailability, targeted delivery, and controlled release, enhancing therapeutic efficacy and reducing side effects. They are also used in cancer therapy, gene delivery, and vaccination. Nanomaterial-based biosensors detect biomolecules at ultra-low concentrations, enhancing disease diagnosis and monitoring. In tissue engineering, nanomaterials create scaffolds mimicking the extracellular matrix, promoting cell adhesion, proliferation, and differentiation. Techniques like electrospinning and 3D printing are used to create bioactive scaffolds for regenerative medicine. This chapter highlights the transformative potential of nanomaterials in biomedical applications, addressing challenges and future directions in this rapidly evolving field.

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Nanomaterials and Scaffolds for Tissue Engineering and Regenerative Medicine

Cited by 3 publications

References 183 publications

Polymeric Theragnostic Nanoplatforms for Bone Tissue Engineering

Polymeric Theragnostic Nanoplatforms for Bone Tissue Engineering

Nanomaterials for Biomedical Applications

Synergistic Effects of Nanomaterials in Drug Delivery, Biosensing, and Tissue Engineering

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