Nanomaterials as multimodal photothermal agents (PTAs) against ‘Superbugs’

Roy, Shubham; Roy, Jhilik; Guo, Bing

doi:10.1039/d2tb02396b

Cited by 16 publications

(6 citation statements)

References 139 publications

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“…The high-frequency capacitance (Figure 2e) corresponds to geometric capacitance that signifies charge accumulation at the interfaces, while the semicircles of the Nyquist plots (Figure 2f) can be attributed to recombination resistance (R rec ) of the material. [24] It can be seen that PSC with the bilayer structure has lower capacitance and larger R rec than that of the single-layer device, suggesting that the charge accumulation and recombination in such devices have been suppressed. Consequently, the V oc loss has been reduced.…”

Section: Effect Of the Heterojunction Structurementioning

confidence: 98%

Improved Performance of Lead‐Free Perovskite Solar Cells Based on Multi‐Absorber MASnI₃/CsGeI₃ Heterojunction by Device Simulation

Huang,

Yang,

et al. 2024

Advcd Theory and Sims

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Lead‐free perovskite solar cell (PSC) is the direction of future development of PSCs due to its reduced toxicity. However, the power conversion efficiency (PCE) of the lead‐free PSCs is still lagging behind their lead‐based counterparts, which hinders their further application. Multi‐absorber approach can effectively overcome this problem as it allows the maximum utilization of solar spectrum. Therefore, in this study a novel lead‐free MASnI3/CsGeI3 heterojunction structure is proposed to boost the performance of PSCs based on single CsGeI3 absorption layer. The critical device parameters including absorber thickness, defect density, doping concentration, and back contact work function are studied and optimized using the numerical software SCAPS‐1D. Under optimized conditions, PSCs based on Sn/Ge bilayer structure yield a considerable PCE of 16.15%, significantly higher than the single CsGeI3 based PSCs (optimized PCE of 7.43%) with higher thermal stability. The simulation results indicate a huge potential of the proposed multi‐absorber heterojunction structure for highly efficient lead‐free PSCs, which will contribute to achieving clean and sustainable energy in the future.

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Section: Effect Of the Heterojunction Structurementioning

confidence: 98%

Improved Performance of Lead‐Free Perovskite Solar Cells Based on Multi‐Absorber MASnI₃/CsGeI₃ Heterojunction by Device Simulation

Huang,

Yang,

et al. 2024

Advcd Theory and Sims

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“…Hazardous chemicals, pesticides, and herbicides from industries, farms, homes, and commercial areas can cause acute toxicity and immediate death or chronic toxicity that can lead to neurological problems or even cancers. 2 Solid wastes discharged into the water are comparatively easier to treat or remove, whereas it is a difficult challenge for scientists and the government to deal with liquid waste. 3 Moreover, the proper treatment and removal of pathogenic contamination are currently a matter of concern.…”

Section: Introductionmentioning

confidence: 99%

“…Water pollutants are not only responsible for the spread of a wide range of ailments but also have toxic impacts on aquatic habitats and human beings. Hazardous chemicals, pesticides, and herbicides from industries, farms, homes, and commercial areas can cause acute toxicity and immediate death or chronic toxicity that can lead to neurological problems or even cancers . Solid wastes discharged into the water are comparatively easier to treat or remove, whereas it is a difficult challenge for scientists and the government to deal with liquid waste .…”

Section: Introductionmentioning

confidence: 99%

Natural Clay-Modified Piezocatalytic Membrane for Efficient Removal of Coliform Bacteria from Wastewater

Mondal,

Bag,

Roy

et al. 2024

Langmuir

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In the modern era, water pollution, especially from industries, agricultural farms, and residential areas, is caused by the release of a large scale of heavy metals, organic pollutants, chemicals, etc., into the environment, posing a serious threat to aquatic ecosystems and nature. Moreover, untreated sewage waste discharged directly into nearby water bodies can cause various diseases to mankind due to the high load of fecal coliform bacteria. This work demonstrates the development of a biocompatible, cost-effective, highly robust, efficient, flexible, freestanding, and reusable membrane using naturally formed biocompatible kaolinite clay-doped poly(vinylidene fluoride-hexafluoropropylene) (PVDF-HFP) for effective piezodynamic destruction of coliform bacteria. In this study, Escherichia coli (E. coli) and Enterococcus faecalis (E. faecalis) have been used to evaluate the mechanical stimulus-responsive antibacterial efficacy of the nanocomposite membrane. The membrane can effectively eradicate nearly 99% viable E. coli and 97% E. faecalis within a span of 40 min under mechanical stimulation (soft ultrasound ∼15 kHz). To further understand the mechanism, an evaluation of reactive oxygen species and bacterial FESEM was performed. These studies revealed that bacterial cells suffered severe visible cell damage after 40 min of piezocatalysis, elucidating the fact that the synthesized membrane is capable of producing a superior piezodynamic antibacterial effect.

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“…In recent years, many nanoparticle-mediated antimicrobial therapies have been reported to eliminate bacterial infections. − Among antibacterial materials, nitric oxide (NO) is a potent broad-spectrum antibacterial agent, which can trigger nitrosative and oxidative stress within the tolerable concentration range by reacting with free radical superoxide to generate reactive byproducts. − In this case, the nitrosative leads to thiols nitrosylation and DNA deamination, while the oxidative stress results in membrane damage. − More significantly, recent reports suggest that NO can disperse and eliminate biofilms at low and high concentrations through the intracellular second messenger cyclic di-GMP, respectively. , In addition to the antibacterial ability, NO accelerates wound healing by regulating cell proliferation, wound contraction, and tissue remodeling . Despite these promising benefits, there is a major challenge in the sustainable supply of NO at the wound site.…”

Section: Introductionmentioning

confidence: 99%

Sustained Endogenous Nitric Oxide Catalytic System Endows Skin Scaffolds with Antibiofilm and Antibacterial Activities

Yang,

Li,

Chen

et al. 2023

ACS Appl. Polym. Mater.

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Infection is the main obstacle to wound repair and usually requires clinical intervention to kill bacteria, while the formed bacterial biofilms protect bacteria against antibacterial treatments. Nitric oxide (NO) therapy is a potential strategy for disrupting biofilms, which encounters a major challenge in the sustainable supply of NO at the wound site. Herein, a nitric oxide catalytic system (Cu@ZIF-8) is constructed by doping Cu 2+ ions on zeolitic imidazolate framework-8 (ZIF-8) via coordination between Cu 2+ ions and dimethylimidazole groups on ZIF-8. Cu@ZIF-8 is then incorporated into poly(p-dioxanone) (PPDO) to prepare a porous skin scaffold, which allows the slow-controlled release of Cu 2+ ions. In this case, the control-released Cu 2+ ions catalyze S-nitrosothiols (RSNOs) enriched at the wound site to continuously supply endogenous NO. NO then reacts with oxygen and free radical superoxide to form reactive nitrogen species to eliminate bacterial biofilms and trigger nitrosative and oxidative stress to kill bacteria. Results showed that the scaffold could continuously release Cu 2+ and catalyze RSNOs to produce NO for more than 28 days, demonstrating the sustainable release ability of NO. The biofilms of Escherichia coli and Staphylococcus aureus cocultured with the scaffold were eliminated by 79.8 and 79.3%, respectively. Moreover, the scaffold showed robust antibacterial activity against E. coli and S. aureus. This study provided an efficient therapy on infection-impaired skin by catalyzing the endogenous donor to produce NO for eliminating biofilms and improving antibacterial activities.

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Nanomaterials as multimodal photothermal agents (PTAs) against ‘Superbugs’

Abstract: Superbugs, also known as multidrug-resistant bacteria, have become a lethal and persistent threat due to their unresponsiveness toward conventional antibiotics. The main reason being superbugs can rapidly mutate and restrict...

Cited by 16 publications

References 139 publications

Improved Performance of Lead‐Free Perovskite Solar Cells Based on Multi‐Absorber MASnI₃/CsGeI₃ Heterojunction by Device Simulation

Improved Performance of Lead‐Free Perovskite Solar Cells Based on Multi‐Absorber MASnI₃/CsGeI₃ Heterojunction by Device Simulation

Natural Clay-Modified Piezocatalytic Membrane for Efficient Removal of Coliform Bacteria from Wastewater

Sustained Endogenous Nitric Oxide Catalytic System Endows Skin Scaffolds with Antibiofilm and Antibacterial Activities

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Nanomaterials as multimodal photothermal agents (PTAs) against ‘Superbugs’

Abstract: Superbugs, also known as multidrug-resistant bacteria, have become a lethal and persistent threat due to their unresponsiveness toward conventional antibiotics. The main reason being superbugs can rapidly mutate and restrict...

Cited by 16 publications

References 139 publications

Improved Performance of Lead‐Free Perovskite Solar Cells Based on Multi‐Absorber MASnI3/CsGeI3 Heterojunction by Device Simulation

Improved Performance of Lead‐Free Perovskite Solar Cells Based on Multi‐Absorber MASnI3/CsGeI3 Heterojunction by Device Simulation

Natural Clay-Modified Piezocatalytic Membrane for Efficient Removal of Coliform Bacteria from Wastewater

Sustained Endogenous Nitric Oxide Catalytic System Endows Skin Scaffolds with Antibiofilm and Antibacterial Activities

Contact Info

Product

Resources

About

Improved Performance of Lead‐Free Perovskite Solar Cells Based on Multi‐Absorber MASnI₃/CsGeI₃ Heterojunction by Device Simulation

Improved Performance of Lead‐Free Perovskite Solar Cells Based on Multi‐Absorber MASnI₃/CsGeI₃ Heterojunction by Device Simulation