Nanomaterials-based biosensor and their applications: A review

Malik, Sumit; Singh, Joginder; Goyat, Rohit; Saharan, Yajvinder; Chaudhry, Vivek; Umar, Ahmad; Ibrahim, Ahmed A.; Akbar, Sheikh; Ameen, Sadia; Baskoutas, Sotirios

doi:10.1016/j.heliyon.2023.e19929

Cited by 97 publications

(25 citation statements)

References 209 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Such sensors are highly suitable for point-of-care diagnostics and real-time monitoring owing to their rapid response times. , The multifunctionality of 2D-nanomaterial surfaces enables the immobilization of diverse recognition elements, permitting the simultaneous detection of various biomolecules. This aspect, coupled with improved specificity and reduced false positives, contributes to the diagnostic accuracy of such systems. , Furthermore, the facile miniaturization of 2D-nanomaterial-based biosensors makes them suitable for the fabrication of portable and wearable devices. The high surface area of 2D-based nanomaterials, which enables the fabrication of sensors with low detection limits that can identify biomarkers at extremely low concentrations, makes 2D nanomaterials invaluable for the development of sensitive and efficient diagnostic tools for a wide range of biomedical applications. − …”

Section: Properties Of 2d Nanomaterials Used In Healthcare Applicationsmentioning

confidence: 99%

“…This aspect, coupled with improved specificity and reduced false positives, contributes to the diagnostic accuracy of such systems. 69,70 Furthermore, the facile miniaturization of 2D-nanomaterialbased biosensors makes them suitable for the fabrication of portable and wearable devices. The high surface area of 2Dbased nanomaterials, which enables the fabrication of sensors with low detection limits that can identify biomarkers at extremely low concentrations, makes 2D nanomaterials invaluable for the development of sensitive and efficient diagnostic tools for a wide range of biomedical applications.…”

Section: Healthcare Applicationsmentioning

confidence: 99%

See 1 more Smart Citation

Recent Advances in Two-Dimensional Nanomaterials for Healthcare Monitoring

Manoharan,

Batcha,

Mahalingam

et al. 2024

ACS Sens.

View full text Add to dashboard Cite

The development of advanced technologies for the fabrication of functional nanomaterials, nanostructures, and devices has facilitated the development of biosensors for analyses. Two-dimensional (2D) nanomaterials, with unique hierarchical structures, a high surface area, and the ability to be functionalized for target detection at the surface, exhibit high potential for biosensing applications. The electronic properties, mechanical flexibility, and optical, electrochemical, and physical properties of 2D nanomaterials can be easily modulated, enabling the construction of biosensing platforms for the detection of various analytes with targeted recognition, sensitivity, and selectivity. This review provides an overview of the recent advances in 2D nanomaterials and nanostructures used for biosensor and wearable-sensor development for healthcare and healthmonitoring applications. Finally, the advantages of 2D-nanomaterial-based devices and several challenges in their optimal operation have been discussed to facilitate the development of smart highperformance biosensors in the future.

show abstract

Section: Properties Of 2d Nanomaterials Used In Healthcare Applicationsmentioning

confidence: 99%

Section: Healthcare Applicationsmentioning

confidence: 99%

Recent Advances in Two-Dimensional Nanomaterials for Healthcare Monitoring

Manoharan,

Batcha,

Mahalingam

et al. 2024

ACS Sens.

View full text Add to dashboard Cite

show abstract

“…The exceptional adaptability of SWCNTs encompasses various domains, including chemical and biological sensing applications, as well as the emerging realm of wearable technology. 175 In this context, SWCNTs hold significant potential in the advancement of smart fabrics that possess the ability to monitor health conditions.…”

Section: Chirality-sorted/monochiral Swcntsmentioning

confidence: 99%

Understanding the Molecular Assemblies of Single Walled Carbon Nanotubes and Tailoring their Photoluminescence for the Next-Generation Optical Nanosensors

Sultana,

Dewey,

Arellano

et al. 2024

Chem. Mater.

View full text Add to dashboard Cite

Interest in optical materials for biomedical imaging and sensing applications has grown significantly in recent decades. Among a variety of material choices, single-walled carbon nanotubes (SWCNTs) are emerging materials for molecular imaging, sensing, and optoelectronic applications due to their nonphotobleaching photoluminescence in the tissue-transparent near-infrared spectral window. However, pristine SWCNTs need surface functionalization to render them soluble in biofriendly media and facilitate their interaction with target analytes. Understanding the functionalization of SWCNTs and the structures of their resulting molecular assemblies plays a pivotal role in yielding efficient optical probes and sensors. Studies have shown that the size, composition, configuration, and concentration of functionalizing compounds on the nanotube surface can affect the nanotube dispersions and optical characteristics. Herein, we review recent progress in the design, synthesis, and applications of SWCNT-based optical nanosensors. An overview of nanotube structure, functionalization, suspension of SWCNTs in solutions with various dispersants, and their molecular assemblies presented from molecular dynamics simulation studies is provided. We further discuss how these assemblies along with solvent dielectric affect nanotube dispersion efficiencies, their role in a nanotube's optical response to a change in its local environment, and how a nanotube's optical properties are utilized for sensor development.

show abstract

“…[144] The use of NPs in biosensors were discussed in some other recent reviews in details, and we refer the readers to these papers. [145][146][147][148] 6. Conclusion and Future Perspective…”

Section: Biomedical Sensing Using Peptide-modified Nanoparticlesmentioning

confidence: 99%

Peptide‐conjugated Nanoparticle Platforms for Targeted Delivery, Imaging, and Biosensing Applications

Ilieş,

Yildiz,

Abbas

2024

ChemBioChem

View full text Add to dashboard Cite

Peptides have become an indispensable tool in engineering of multifunctional nanostructure platforms for biomedical applications such as targeted drug and gene delivery, imaging and biosensing. They can be covalently incorporated into a variety of nanoparticles (NPs) including polymers, metallic nanoparticles, and others. Using different bioconjugation techniques, multifunctional peptide‐modified NPs can be formulated to produce therapeutical and diagnostic platforms offering high specificity, lower toxicity, biocompatibility, and stimuli responsive behavior. Targeting peptides can direct the nanoparticles into specific tissues for targeted drug and gene delivery and imaging applications due to their specificity towards certain receptors. Furthermore, due to their stimuli‐responsive features, they can offer controlled release of therapeutics into desired sites of disease. In addition, peptide‐based biosensors and imaging agents can provide non‐invasive detection and monitoring of diseases including cancer, infectious diseases, and neurological disorders. In this review, we covered the design and formulation of recent peptide‐based NP platforms, as well as their utilization in in vitro and in vivo applications such as targeted drug and gene delivery, targeting, sensing, and imaging applications. In the end, we provided the future outlook to design new peptide conjugated nanomaterials for biomedical applications.

show abstract

Nanomaterials-based biosensor and their applications: A review

Cited by 97 publications

References 209 publications

Recent Advances in Two-Dimensional Nanomaterials for Healthcare Monitoring

Recent Advances in Two-Dimensional Nanomaterials for Healthcare Monitoring

Understanding the Molecular Assemblies of Single Walled Carbon Nanotubes and Tailoring their Photoluminescence for the Next-Generation Optical Nanosensors

Peptide‐conjugated Nanoparticle Platforms for Targeted Delivery, Imaging, and Biosensing Applications

Contact Info

Product

Resources

About