Cinnamon, a popular spice known for its aromatic properties and medicinal benefits, has recently gained attention in the field of biomedical research for its potential to develop advanced hydrogels. Hydrogels are three-dimensional polymeric networks that can absorb and retain significant amounts of water, making them highly suitable for various biomedical applications. This comprehensive analysis delves into the potential of cinnamon-induced hydrogels, exploring their synthesis, characterization, biocompatibility, and safety evaluation. Furthermore, the article explores the diverse range of advanced biomedical applications that cinnamon-based hydrogels can offer, including wound healing, tissue regeneration, drug delivery systems, and biomedical imaging. Additionally, the challenges and future perspectives of developing cinnamon-induced hydrogels for biomedical applications are discussed, shedding light on the optimization and commercialization potential of this innovative biomaterial.