Nanomaterials in combating cancer: Therapeutic applications and developments

Targeted delivery of mesoporous silica nanoparticles loaded monastrol into cancer cells: an in vitro study

“…Efficient drug delivery is very essential for enhancing diagnosis, reducing side effects and drug efficacy. Nanoparticles offer a capable approach towards delivering the therapeutic agents to the targeted organs and their use in cancer treatment (Nazir et al 2014;Chen et al 2016;Rosenholm et al 2011;Wilczewska et al 2012;Sahoo et al 2007;Suri et al 2007). Mesoporous silica nanoparticles are considered to be very promising candidate for drug delivery specifically for water-insoluble drug.…”

GdDOTAGA(C18)2: an efficient amphiphilic Gd(iii) chelate for the preparation of self-assembled high relaxivity MRI nanoprobes

“…1,2 The versatility of nanosystems allows tuneable surface modification and loading with different chemicals (drugs, imaging agents, targeting vectors) with the aim of fine-optimizing the biological properties of the nanocarriers, while simultaneously enabling them to perform diagnostically and/or therapeutically important functions. 3,4 Lipid-containing nanoparticles (LNPs), 5 like micelles, liposomes, and solid lipid nanoparticles, or other similar nanosystems (such as the recently developed dendrimersomes) [6][7][8] are based on supramolecular aggregates obtained by spontaneous assembling in aqueous solution of phospholipids alone or in mixture with other amphiphilic molecules. Such objects have been frequently used as nanocarriers for drug delivery and imaging applications due to their great chemical versatility that allows the loading of hydrophobic, amphiphilic, and hydrophilic substances, and surface decoration with targeting vectors, blood lifetime modulators, and diagnostic agents.…”

The Toxic Effects of Nanoparticles on Male Reproductive System: Review

“…NP'ler, kimyasal ve fiziksel özellikleri ile madde özgül-lüğü açısından aynı maddenin daha büyük ölçekli yapısından ayırt edilebilmektedir. 1,2 Nanomateryaller, özellikle sağlık ve tarım alanlarında önemli uygulamalarda kullanılmakta-dır.…”