Nanomedicine: Advancement in healthcare

Mago, Arpit; Tahir, Muhammad Junaid; Khan, Muhammad Arslan; Ahmed, Khabab Abbasher Hussien Mohamed; Munir, Muhammad Usman

doi:10.1016/j.amsu.2022.104078

Cited by 6 publications

(2 citation statements)

References 10 publications

(10 reference statements)

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“…Additionally, nanomedicine can be optimized to enter target cells, an advantage of their comparatively small particle size. Nanomedicine also have the advantages of high drug loading rates and targeting ability, which can prevent effects on healthy tissues [ 33 ]. In retrospect, nanomaterials had a long history of medical use during ancient times.…”

Section: Nanomedicine Delivery Systems Of Mineral and Phytomedicinementioning

confidence: 99%

“…Nanotechnologies could improve efficacy, increase drug stability, and provide greater flexibility of form and multiple drug delivery routes for Traditional Chinese medicine [ 31 ]. Their advantages include the ability to realize sustained release, increase the biological half-life, and prolong the circulation time in the body [ 32 , 33 ]. Since phytomedicine has been useful in treating epidemic diseases for a long time in Chinese history, the accumulated experience has led to success for AML treatment in terms of alleviating clinical symptoms, increasing the cure rate of disease, and hindering disease progression [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

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Recent advance in phytonanomedicine and mineral nanomedicine delivery system of the treatment for acute myeloid leukemia

et al. 2023

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Acute myeloid leukemia (AML) is an invasive hematopoietic malignancy caused by excessive proliferation of myeloblasts. Classical chemotherapies and cell transplantation therapies have remarkable efficacy in AML treatment; however, 30–40% of patients relapsed or had refractory disease. The resistance of AML is closely related to its inherent cytogenetics or various gene mutations. Recently, phytonanomedicine are found to be effective against resistant AML cells and have become a research focus for nanotechnology development to improve their properties, such as increasing solubility, improving absorption, enhancing bioavailability, and maintaining sustained release and targeting. These novel phytonanomedicine and mineral nanomedicine, including nanocrystals, nanoemulsion, nanoparticles, nanoliposome, and nanomicelles, offer many advantages, such as flexible dosages or forms, multiple routes of administration, and curative effects. Therefore, we reviewed the application and progress of phytomedicine in AML treatment and discussed the limitations and future prospects. This review may provide a solid reference to guide future research on AML treatment.

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Section: Nanomedicine Delivery Systems Of Mineral and Phytomedicinementioning

confidence: 99%