“…Various strategies to solubilize water-insoluble drugs have been tried, which include using cosolvent (Malick et al, 2007) or surfactants (Strickley, 2004), solid dispersion (Janssens and Van den Mooter, 2009), inclusion complex ( Van de Manakker et al, 2009), salt formation (Elder et al, 2010) or colloidal systems such as microemulsion (He et al, 2010), micelles (Trivedi et al, 2010), polymeric nano-/micro-particles (Kumari et. al, 2009 ), liposomes (Cukierman and Khan, 2010), emulsions (Mirtallo et al, 2010) and solid lipid nanoparticles (SLNs) (Souto and Müller, 2010).…”