Nanomolar simultaneous determination of levodopa and serotonin at a novel carbon ionic liquid electrode modified with Co(OH)2 nanoparticles and multi-walled carbon nanotubes

Babaei, Ali; Taheri, Alireza; Aminikhah, Majid

doi:10.1016/j.electacta.2012.11.121

Cited by 70 publications

(46 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To increase the selectivity of serotonin in the presence of ascorbic acid and uric acid, another study introduced Nafion into a Co(OH) 2 -MWCNT-modified CILE. [84] Nafion made the sensor impermeable to ascorbic acid and uric acid and improved the selectivity to the cationic neurochemicals l-dopa and serotonin, which were detected in human serum. Advantages of CN-IL based microelectrodes include the electrocatalytic effects and the simple preparation procedure.…”

Section: 0 Neurotransmitters/neurochemicalsmentioning

confidence: 99%

Recent trends in carbon nanomaterial-based electrochemical sensors for biomolecules: A review

Yang

Denno

Pyakurel

et al. 2015

Analytica Chimica Acta

494

263

View full text Add to dashboard Cite

Carbon nanomaterials are advantageous for electrochemical sensors because they increase the electroactive surface area, enhance electron transfer, and promote adsorption of molecules. Carbon nanotubes (CNTs) have been incorporated into electrochemical sensors for biomolecules and strategies have included the traditional dip coating and drop casting methods, direct growth of CNTs on electrodes and the use of CNT fibers and yarns made exclusively of CNTs. Recent research has also focused on utilizing many new types of carbon nanomaterials beyond CNTs. Forms of graphene are now increasingly popular for sensors including reduced graphene oxide, carbon nanohorns, graphene nanofoams, graphene nanorods, and graphene nanoflowers. In this review, we compare different carbon nanomaterial strategies for creating electrochemical sensors for biomolecules. Analytes covered include neurotransmitters and neurochemicals, such as dopamine, ascorbic acid, and serotonin; hydrogen peroxide; proteins, such as biomarkers; and DNA. The review also addresses enzyme-based electrodes that are used to detect non-electroactive species such as glucose, alcohols, and proteins. Finally, we analyze some of the future directions for the field, pointing out gaps in fundamental understanding of electron transfer to carbon nanomaterials and the need for more practical implementation of sensors.

show abstract

Section: 0 Neurotransmitters/neurochemicalsmentioning

confidence: 99%

Recent trends in carbon nanomaterial-based electrochemical sensors for biomolecules: A review

Yang

Denno

Pyakurel

et al. 2015

Analytica Chimica Acta

494

263

View full text Add to dashboard Cite

show abstract

“…As a result, it is very important to develop a method for the simultaneous determination of L-dopa and ST 26. Fig.…”

mentioning

confidence: 99%

“…Low levels of ST have been associated with several disorders, notably depression, migraine, bipolar disorder and anxiety. 26 The application of the electrochemical methods for the determination of catecholamine neurotransmitters have attracted great interests due to their simplicity, rapidness, high sensitivity and the ability of sensing neurotransmitters in living organisms and in vivo real time analysis. 24,28,29 However, electrochemical analysis at the unmodified electrodes suffer from some problems such as; slow electron transfer, high overpotential, overlapping voltammetric peaks, surface fouling and high detection limits.…”

mentioning

confidence: 99%

The Electrochemistry and Determination of Some Neurotransmitters at SrPdO₃Modified Graphite Electrode

Atta

Ali

El-Ads

et al. 2013

J. Electrochem. Soc.

View full text Add to dashboard Cite

Graphite/SrPdO 3 was utilized for the sensitive determination of some neurotransmitters, namely dopamine (DA), epinephrine (EP), norepinephrine (NE), serotonin (ST), 3,4-dihydroxyphenylacetic acid (DOPAC) and L-dopa. Graphite/SrPdO 3 exhibited higher electrocatalytic activity toward the studied neurotransmitters compared to bare graphite. It was confirmed that graphite electrode was more suitable substrate for immobilization of SrPdO 3 perovskite compared to other surfaces. Moreover, simultaneous determinations of L-dopa, ascorbic acid (AA) and uric acid (UA) or ST were achieved with large peak potential separation. The linear response for L-dopa was obtained in the range of 0.6 μmol L −1 to 9 μmol L −1 with correlation coefficient 0.996 and detection limit 1.63 nmol L −1 . The proposed composite sensor exhibited high reproducibility, enhanced sensitivity, selectivity, anti-interference ability, unique long-term stability (over two months) and applicability in the human urine samples with satisfying results.

show abstract

“…[1][2][3][4][5][6][7][8] Low levels of 5-HT have been associated with several disorders, notably depression, migraine, eating disorders, obsessive-compulsive disorder and anxiety. 9,10 Thus detecting and determining the concentrations of serotonin and their metabolites in the presence of interfering species is an important goal in electrochemical analysis.…”

mentioning

confidence: 99%

Development and Application of the Serotonin Voltametric Sensors Based on Molecularly Imprinting Technology

Wang

et al. 2015

J. Electrochem. Soc.

View full text Add to dashboard Cite

A novel modified glassy carbon electrode was prepared as an electrochemical voltammetric sensor based on molecularly imprinted polymer film for serotonin detection. The sensitive film was prepared by co-polymerization of 5-hydroxy tryptophan (5-HTP) and acrylamide (AM) on the carbon nanotubes modified glassy carbon electrode. The surface morphologies of the modified electrodes were characterized by scanning electron microscope. The electrochemical behavior of serotonin molecules on the imprinted electrode was studied by differential pulse voltammetry (DPV), cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). Under the optimum conditions, the linear relationships between current and concentration were obtained in the range from 1.8 × 10 −6 to 5.4 × 10 −9 mol L −1 , with the linear regression equation Ip = 1.552 C + 8.778 × 10 −8 (I: μA, C: μmol L −1 ), correlation coefficient 0.9997. The detection limit of 1.8 × 10 −10 mol L −1 was achieved (S/N = 3). The applicability of the modified electrode was demonstrated by determination of serotonin in human serum. Moreover, the possible oxidation mechanism of 5-HT was discussed.

show abstract

Nanomolar simultaneous determination of levodopa and serotonin at a novel carbon ionic liquid electrode modified with Co(OH)2 nanoparticles and multi-walled carbon nanotubes

Cited by 70 publications

References 49 publications

Recent trends in carbon nanomaterial-based electrochemical sensors for biomolecules: A review

Recent trends in carbon nanomaterial-based electrochemical sensors for biomolecules: A review

The Electrochemistry and Determination of Some Neurotransmitters at SrPdO₃Modified Graphite Electrode

Development and Application of the Serotonin Voltametric Sensors Based on Molecularly Imprinting Technology

Contact Info

Product

Resources

About

Nanomolar simultaneous determination of levodopa and serotonin at a novel carbon ionic liquid electrode modified with Co(OH)2 nanoparticles and multi-walled carbon nanotubes

Cited by 70 publications

References 49 publications

Recent trends in carbon nanomaterial-based electrochemical sensors for biomolecules: A review

Recent trends in carbon nanomaterial-based electrochemical sensors for biomolecules: A review

The Electrochemistry and Determination of Some Neurotransmitters at SrPdO3Modified Graphite Electrode

Development and Application of the Serotonin Voltametric Sensors Based on Molecularly Imprinting Technology

Contact Info

Product

Resources

About

The Electrochemistry and Determination of Some Neurotransmitters at SrPdO₃Modified Graphite Electrode