Pharmaceutical Nanotechnology: Innovation and Production 2016
DOI: 10.1002/9783527800681.ch17
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Nanoparticle Toxicity: General Overview and Insights Into Immunological Compatibility

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Cited by 2 publications
(1 citation statement)
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“…DRA studies with ENPs, however, suggest that the toxicity of some ENPs is not mass dependent, but influenced by other physico-chemical characteristics (e.g., surface area, chemical composition, and particle morphology) [31]. Several studies found that the toxicity of lowsoluble ENPs was better described by their surface area than by their total mass [30], number of particles [32], functional groups [33]. Despite these findings, however, it is still largely unknown which properties influence the toxicity of most ENPs and this gap in knowledge is partly attributable to the fact that the tested ENPs are seldom well characterized [19].…”
Section: Risk Assessment Of Engineered Nanoparticlesmentioning
confidence: 99%
“…DRA studies with ENPs, however, suggest that the toxicity of some ENPs is not mass dependent, but influenced by other physico-chemical characteristics (e.g., surface area, chemical composition, and particle morphology) [31]. Several studies found that the toxicity of lowsoluble ENPs was better described by their surface area than by their total mass [30], number of particles [32], functional groups [33]. Despite these findings, however, it is still largely unknown which properties influence the toxicity of most ENPs and this gap in knowledge is partly attributable to the fact that the tested ENPs are seldom well characterized [19].…”
Section: Risk Assessment Of Engineered Nanoparticlesmentioning
confidence: 99%