Nanoparticles as a Solution for Eliminating the Risk of Mycotoxins

Horký, Pavel; Skaličková, Sylvie; Baholet, Daria; Skládanka, Jiří­

doi:10.3390/nano8090727

Cited by 115 publications

(82 citation statements)

References 175 publications

(145 reference statements)

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“…In an attempt to mitigate the risk of mycotoxin contamination in food and feed, different pre-and post-harvest physical (e.g., crop rotation, thermal treatment, and irradiation), chemical (e.g., acids/bases and absorbents), and biological (e.g., microbial and enzymatic degradation) strategies have been deployed [27,[204][205][206][207]. Besides these conventional mitigation methods, nanotechnology may be an innovative solution to mycotoxin contamination [208]. It is not possible in this review to discuss all the approaches; instead, the discussion will focus on remediation strategies that are most widely used in the animal feed industry, especially the use of mycotoxin adsorbents as feed additives.…”

Section: Strategies To Counteract Mycotoxin Contaminationmentioning

confidence: 99%

In-Vitro Cell Culture for Efficient Assessment of Mycotoxin Exposure, Toxicity and Risk Mitigation

Karrow

Shandilya

et al. 2020

Toxins

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Mycotoxins are toxic secondary fungal metabolites that commonly contaminate crops and food by-products and thus, animal feed. Ingestion of mycotoxins can lead to mycotoxicosis in both animals and humans, and at subclinical concentrations may affect animal production and adulterate feed and animal by-products. Mycotoxicity mechanisms of action (MOA) are largely unknown, and co-contamination, which is often the case, raises the likelihood of mycotoxin interactions. Mitigation strategies for reducing the risk of mycotoxicity are diverse and may not necessarily provide protection against all mycotoxins. These factors, as well as the species-specific risk of toxicity, collectively make an assessment of exposure, toxicity, and risk mitigation very challenging and costly; thus, in-vitro cell culture models provide a useful tool for their initial assessment. Since ingestion is the most common route of mycotoxin exposure, the intestinal epithelial barrier comprised of epithelial cells (IECs) and immune cells such as macrophages, represents ground zero where mycotoxins are absorbed, biotransformed, and elicit toxicity. This article aims to review different in-vitro IEC or co-culture models that can be used for assessing mycotoxin exposure, toxicity, and risk mitigation, and their suitability and limitations for the safety assessment of animal foods and food by-products.

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Section: Strategies To Counteract Mycotoxin Contaminationmentioning

confidence: 99%

In-Vitro Cell Culture for Efficient Assessment of Mycotoxin Exposure, Toxicity and Risk Mitigation

Karrow

Shandilya

et al. 2020

Toxins

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show abstract

“…It has been reported that selenium (Se) application decreases Cd uptake [75]. In similar studies, selenium, copper, zinc oxide and many other metallic nanoparticles [92][93][94][95][96][97][98] have been studied in food processing, packaging and preservation against phytopathogens and rodents. The washing with water or soaking in solutions of salt and some chemicals e.g.…”

Section: Recommendationsmentioning

confidence: 99%

Chemical Residues in Food Grains: The Burning Health Issues in Asian Countries

2019

JAHR

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Food security is a high-priority issue for sustainable global development both quantitatively and qualitatively. Once pesticides are applied, residues may be found in soil, on plant, on harvested product, on application equipment, in water and irrigation canals, in pesticide storage area, on cloth of applicant. Short term poisoning effects like nausea, vomiting, headache, chest pain, eye, skin and throat irritation etc. and potential long-term health effect like allergies, cancer, nervous system damage, birth defects, reproductive problem have been reported in recent decades, adverse effects of unexpected contaminants on crop quality have threatened both food security and human health. Heavy metals, metalloids (e.g., Hg, As, Pb, Cd, and Cr) from pesticides and fertilizers can jeopardize human metabolomics, contributing to morbidity and even mortality. Those during crop production include soil nutrient depletion, water depletion, soil and water contamination, and pest resistance/outbreaks and the emergence of new pests and diseases.

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“…Mycotoxins are toxic secondary metabolites produced by several mold fungi, whose occurrence in food and feed cause deleterious health effects on humans and poultry. Yeast cell walls, clay binders, and antioxidant additives are the most widely used products to eliminate mycotoxin and to reduce their harmful effect (Horky et al, 2018). B. cinerea culture filtrates may induce toxic effects when applied to plant tissue (Elad, 2004).…”

Section: Mycotoxinsmentioning

confidence: 99%

Disease cycle and infection strategies of systemic plant pathogen Botrytis cinerea

S.M.

A.Y.

S.B.

et al. 2019

Novel Research in Microbiology Journal

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Botrytis cinerea is a ubiquitous filamentous fungal pathogen of a wide range of plant species. This fungus is able to infect all aerial parts of its host plants; where infection may cause enormous damage both during plant growth and in the post-harvest stage (during cold storage or transport). B. cinerea is a major cause of economic losses in the production chain of cut flowers, bulb flowers and pot plants. Molecular-genetic studies performed over the past decade have provided a wealth of novel insights into the infection mechanisms utilized by this pathogen. Fungal genes important for successful infection by B. cinerea were identified. Such knowledge provided perspectives for designing novel, and rational plant protection strategies that could effectively counteract important pathogen virulence factors. In this study; the infection process will be divided into different stages; moreover, the role of various fungal enzymes and metabolites in the different stages will be discussed. The aim of the current study was to address perspectives for novel control strategies that may reduce and/or delay the damage incited by B. cinerea infection.

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Nanoparticles as a Solution for Eliminating the Risk of Mycotoxins

Cited by 115 publications

References 175 publications

In-Vitro Cell Culture for Efficient Assessment of Mycotoxin Exposure, Toxicity and Risk Mitigation

In-Vitro Cell Culture for Efficient Assessment of Mycotoxin Exposure, Toxicity and Risk Mitigation

Chemical Residues in Food Grains: The Burning Health Issues in Asian Countries

Disease cycle and infection strategies of systemic plant pathogen Botrytis cinerea

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