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The electropolymerization of anthranilic acid (2-aminobenzoic acid) has been shown to lead to the production of a redox polymer functionalized with carboxylate groups capable of complexing metal ions. The polymer was exploited as a means of capturing ferric ion from solution with the iron decorated polymer chains used as seeding points for the formation of Prussian blue (PB). Nanoclusters of PB were dispersed throughout the three-dimensional polymer matrix with deposition achieved through direct electrochemical means or via a dip process. The latter exploited the chemical combination of Fe(III) + Ferrocyanide to yield PB allowing its dispersal of the PB throughout the polymer film. The polymer film and its subsequent modification have been characterized by electron microscopy, X-ray analysis, Raman spectroscopy and electrochemical analysis. The stability toward peroxide has also been explored. Graphical Abstract
The electropolymerization of anthranilic acid (2-aminobenzoic acid) has been shown to lead to the production of a redox polymer functionalized with carboxylate groups capable of complexing metal ions. The polymer was exploited as a means of capturing ferric ion from solution with the iron decorated polymer chains used as seeding points for the formation of Prussian blue (PB). Nanoclusters of PB were dispersed throughout the three-dimensional polymer matrix with deposition achieved through direct electrochemical means or via a dip process. The latter exploited the chemical combination of Fe(III) + Ferrocyanide to yield PB allowing its dispersal of the PB throughout the polymer film. The polymer film and its subsequent modification have been characterized by electron microscopy, X-ray analysis, Raman spectroscopy and electrochemical analysis. The stability toward peroxide has also been explored. Graphical Abstract
Antioxidant nanozymes are powerful tools to combat oxidative stress, which can be further improved by applying nanozyme mixtures of multiple enzymatic function. Here, cocktails of Prussian blue (PB) nanocubes and copper(II) exchanged ZSM-5 zeolites (CuZ) with enhanced reactive oxygen species (ROS) scavenging activity were developed. Surface functionalization of the particles was performed using polymers to obtain stable colloids, i.e., resistant to aggregation, under a wide range of experimental conditions. The nanozyme cocktails possessed advanced antioxidant properties with multiple enzyme-like functions, catalyzing the decomposition of ROS in cascade reactions. The activity of the mixture far exceeded that of the individual particles, particularly in the peroxidase assay, where an improvement of more than an order of magnitude was observed, pointing to coamplification of the enzymatic activity. In addition, it was revealed that the copper(II) site in the CuZ plays an important role in the decomposition of both superoxide radicals and hydrogen peroxide, as it directly catalyzes the former reaction and acts as cocatalyst in the latter process by boosting the peroxidase activity of the PB nanozyme. The results give important insights into the design of synergistic particle mixtures for the broad-spectrum scavenging of ROS to develop efficient tools for antioxidant treatments in both medical therapies and industrial manufacturing processes.
Size-dependent optical and electronic properties are unique characteristics of quantum dots (QDs). A significant advantage is the quantum confinement effect that allows their precise tuning to achieve required characteristics and behavior for the targeted applications. Regarding the aforementioned factors, QDs-based sensors have exhibited dramatic potential for the diverse and advanced applications. For example, QDs-based devices have been potentially utilized for bioimaging, drug delivery, cancer therapy, and environmental remediation. In recent years, use of QDs-based electrochemical sensors have been further extended in other areas like gas sensing, metal ion detection, monitoring of organic pollutants, and detection of radioactive isotopes. Objective of this study is to rationalize the QDs-based electrochemical sensors for state-of-the-art applications. This review article comprehensively illustrates the importance of aforementioned devices along with sources from which QDs devices have been formulated and fabricated. Other distinct features of QDs devices are associated with their extremely high active surfaces, inherent ability of reproducibility, sensitivity, and selectivity for the targeted analyte detection. In this review, major categories of QD materials along with justification of their key roles in electrochemical devices have been demonstrated and discussed. All categories have been evaluated with special emphasis on the advantages and drawbacks/challenges associated with QD materials. However, in the interests of readers and researchers, recent improvements also have been included and discussed. On the evaluation, it has been concluded that despite significant challenges, QDs-based electrochemical sensors exhibit excellent performances for state-of-the-art and targeted applications.
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