Nanoparticles with multiple properties for biomedical applications: A strategic guide

Crozals, Gabriel De; Bonnet, Romaric; Farre, Carole; Chaix, Carole

doi:10.1016/j.nantod.2016.07.002

Cited by 164 publications

(94 citation statements)

References 322 publications

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“…For example, a balance must be drawn between the complexity of the nanomaterial and the time and cost of its synthesis with the increase in efficacy of the cancer treatment it can provide. Not only this, but the size and morphology of the magnetic plasmonic nanoparticles needs to be precisely controlled in order to optimise uptake in vivo-too small (<50 nm) and the nanoparticles are washed out of the body, too large (>300 nm) and they accumulate in the liver and spleen [18].…”

Section: Drug Delivery and Targetingmentioning

confidence: 99%

“…Importantly, all of these steps and processes can be monitored by MRI, CT (computed tomography) and other imaging techniques potentially allowing full control over the medical procedures [10][11][12]. New multimodal magnetic nanostructures have also found applications in molecular-imaging [13,14], as PET-MRI (positron emission tomography-magnetic resonance imaging) contrast agents [15], thermal therapy [16,17] targeted drug delivery and many others [18]. Our review will focus only of the recent developments of magnetic-plasmonic nanocomposites and their biological applications.…”

Section: Introductionmentioning

confidence: 99%

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Multimodal Magnetic-Plasmonic Nanoparticles for Biomedical Applications

2018

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Magnetic plasmonic nanomaterials are of great interest in the field of biomedicine due to their vast number of potential applications, for example, in molecular imaging, photothermal therapy, magnetic hyperthermia and as drug delivery vehicles. The multimodal nature of these nanoparticles means that they are potentially ideal theranostic agents-i.e., they can be used both as therapeutic and diagnostic tools. This review details progress in the field of magnetic-plasmonic nanomaterials over the past ten years, focusing on significant developments that have been made and outlining the future work that still needs to be done in this fast emerging area. The review describes the main synthetic approaches to each type of magnetic plasmonic nanomaterial and the potential biomedical applications of these hybrid nanomaterials.

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Section: Drug Delivery and Targetingmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Multimodal Magnetic-Plasmonic Nanoparticles for Biomedical Applications

2018

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“…The sensor (Figure 12(a)) active area is the thin sensitive semiconductor film (2) of corresponding configuration formed at the semi-insulating GaAs substrate (1). Sensor contacts are formed by the metallization layer (3), which typically is the gold film together with other metals, for example, with titanium sublayer.…”

Section: Use Of the Internet Of Things To Measure Of Magnetic Propertiesmentioning

confidence: 99%

Identification of Fe3O4 Nanoparticles Biomedical Purpose by Magnetometric Methods

Duriagina¹,

Holyaka²,

Tepla³

et al. 2018

Biomaterials in Regenerative Medicine

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The application of magnetic nanoparticles for biomedical research is an interdisciplinary problem. The use of nano-and microsized powder materials as developed technology for obtaining bionanomaterials with magnetocatalytic properties has been investigated. Control over immobilization can be carried by means of magnetic properties. Synthesis of superparamagnetic nanoparticles is developed not only for the benefit of fundamental science, but also for many technologies, such as technologies of magnetic storage media, magnetic ink for printers, but mainly for biosensors and medical applications. All the biomedical applications require that the nanoparticles have high enough levels of saturation of magnetization; their size should be less than 100 nm with a small deviation in size. Appropriate coating of the surface of magnetic nanoparticles should be nontoxic, biocompatible with the target of bioorganic compound. The techniques of measurement of magnetic nanoparticle properties by means of vibrational magnetometers, as well as by means of a set of smart sensor devices in accordance with new concept of Internet of Things (IoTh), were described. The first method is based on vibrating sample magnetometer technique. The second method is based on direct measurement of three dimensions (3D) of nanoparticles' magnetic field components.

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“…Depending on the sizes other properties of nanoparticles as toxicity, adsorption ability and magnetism also change. In particular, when the size of nanoparticles is less than 10 nm they pass into a superparamagnetic state that, when adsorbing the energy of the external high-frequency electromagnetic field, promotes conversion of the energy state into the thermal one [10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%