Nanoporous gold microelectrode arrays using microchips: A highly sensitive and cost-effective platform for electroanalytical applications

Siqueira, Gilvana Pereira; Faria, Lucas Vinícius de; Rocha, Raquel G.; Matias, Tiago A.; Richter, Eduardo M.; Muñoz, Rodrigo A.A.; Silva, Iranaldo Santos da; Dantas, Luiza Maria Ferreira

doi:10.1016/j.jelechem.2022.116880

Cited by 7 publications

(2 citation statements)

References 46 publications

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“…In particular, nanoporous Au (NPA) is an excellent candidate for electrochemical sensor prototypes due to its unique physicochemical properties, bicontinuous porous structure, high surface-to-volume ratios, excellent in-plane conductivity and biocompatibility. 26–30 To date, several methods such as template-based, electroplating replacement and dealloying strategies have been introduced for the preparation of NPA. Among them, the electroplating replacement and dealloying methods have been widely employed due to the simplicity and high efficiency of their preparation processes.…”

Section: Introductionmentioning

confidence: 99%

Unique three-dimensional ordered macroporous dealloyed gold–silver electrochemical sensing platforms for ultrasensitive mercury(ii) monitoring

Jiang,

Zhang,

et al. 2024

Analyst

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Section: Introductionmentioning

confidence: 99%

Unique three-dimensional ordered macroporous dealloyed gold–silver electrochemical sensing platforms for ultrasensitive mercury(ii) monitoring

Jiang,

Zhang,

et al. 2024

Analyst

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“…Dantas and co-workers described the construction of a disposable gold microelectrode array with a gold nanoporous structure. This device was used for the electrochemical detection of inorganic and organic species by square-wave anodic stripping voltammetry [ 19 ]. Compared to these systems, our microfluidic device presents a novel and promising composite for sensing.…”

Section: Introductionmentioning

confidence: 99%

Microfluidic Platform Integrated with Carbon Nanofibers-Decorated Gold Nanoporous Sensing Device for Serum PSA Quantification

et al. 2023

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Prostate cancer is a disease with a high incidence and mortality rate in men worldwide. Serum prostate-specific antigens (PSA) are the main circulating biomarker for this disease in clinical practices. In this work, we present a portable and reusable microfluidic device for PSA quantification. This device comprises a polymethyl methacrylate microfluidic platform coupled with electrochemical detection. The platinum working microelectrode was positioned in the outflow region of the microchannel and was modified with carbon nanofibers (CNF)-decorated gold nanoporous (GNP) structures by the dynamic hydrogen bubble template method, through the simultaneous electrodeposition of metal precursors in the presence of CNF. CNF/GNP structures exhibit attractive properties, such as a large surface to volume ratio, which increases the antibody’s immobilization capacity and the electroactive area. CNFs/GNP structures were characterized by scanning electron microscopy, energy dispersive spectrometry, and cyclic voltammetry. Anti-PSA antibodies and HRP were employed for the immune-electrochemical reaction. The detection limit for the device was 5 pg mL−1, with a linear range from 0.01 to 50 ng mL−1. The coefficients of variation within and between assays were lower than 4.40%, and 6.15%, respectively. Additionally, its clinical performance was tested in serum from 30 prostate cancer patients. This novel device was a sensitive, selective, portable, and reusable tool for the serological diagnosis and monitoring of prostate cancer.

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3D-printed carbon black/polylactic acid electrode modified with silver particles: a powerful alternative and cost-effective sensor for nitrate sensing in real water samples

Alves,

de Faria,

Caldas

et al. 2024

J Solid State Electrochem

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Nanoporous gold microelectrode arrays using microchips: A highly sensitive and cost-effective platform for electroanalytical applications

Cited by 7 publications

References 46 publications

Unique three-dimensional ordered macroporous dealloyed gold–silver electrochemical sensing platforms for ultrasensitive mercury(ii) monitoring

Unique three-dimensional ordered macroporous dealloyed gold–silver electrochemical sensing platforms for ultrasensitive mercury(ii) monitoring

Microfluidic Platform Integrated with Carbon Nanofibers-Decorated Gold Nanoporous Sensing Device for Serum PSA Quantification

3D-printed carbon black/polylactic acid electrode modified with silver particles: a powerful alternative and cost-effective sensor for nitrate sensing in real water samples

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