Nanorobot Movement: Challenges and Biologically inspired solutions

Sharma, Niti Nipun; Mittal, R.K.

doi:10.21307/ijssis-2017-280

Cited by 33 publications

(21 citation statements)

References 79 publications

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“…This motor would need to work in very low Reynolds number conditions, where inertia is irrelevant and swimming by reciprocal motion (a sequence of shapes invariant under time reversal) is not possible. It would be possible to design mechanisms similar to biological motors constituted by either flexible oars (cilia and flagella) or stiff helical shapes associated to an ATP-conducted rotary motor [81]. The efficiency of these machines has been estimated at 1% for bacteria travelling at 30 µm/s (2 × 10 -8 erg/s) [82].…”

Section: Nanosubmarines and Cancer: The Problemsmentioning

confidence: 99%

One Example on How Colloidal Nano- and Microparticles Could Contribute to Medicine

et al. 2009

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Nanomedicine, nowadays, is a popular keyword in the media, although everyone seems to associate it with different visions, hopes and even fears. This article gives a perspective from two sides. From the point of view of a materials scientist, it will be pointed out what new materials will be possible, how they will be designed and which properties they could offer for diagnosis and treatment. From the point of view of a medical doctor, it will be pointed out which properties are actually desired and what materials are hoped for practical applications. The two different points of view indicate that, although sophisticated materials with advanced novel properties will be available in the future, they do not automatically match the requirements and demands of clinicians. The discussion is centerd around one example, multifunctional polyelectrolyte capsules, which might act as a 'nanosubmarine' for in vivo sensing and delivery, which is used to highlight promising interfaces between both disciplines.

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Section: Nanosubmarines and Cancer: The Problemsmentioning

confidence: 99%

One Example on How Colloidal Nano- and Microparticles Could Contribute to Medicine

et al. 2009

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“…hydrolysis of adenosine triphosphate (ATP), a concentration gradient of different ionic species, and an interfacial gradient due to asymmetrical catalytic reactions (Ebbens & Howse 2010). The present review compiles a chronological list of current medical nanorobots (Freitas 1999(Freitas , 2005, design issues (Ummat et al 2005), challenges and solutions (Sharma & Mittal 2008;Ebbens & Howse 2010; related to propulsion, powering, control, and transport of payload to the specific target.…”

Section: Introductionmentioning

confidence: 99%

Propulsion of an artificial nanoswimmer: a comprehensive review

Nain

Sharma

2014

Frontiers in Life Science

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Locomotion at micro and nano scales is a challenge and has drawn attention for over six decades. Inspired by nature, studies have mimicked nanoswimming organisms, which use rotating or beating flagella for locomotion. This mode of propulsion, also known as flagellar propulsion, has been explored extensively in the literature. However, chemical and magnetic methods have gained interest in the last decade owing to advantages including high thrust force and wireless control. The review summarizes chronologically the various propulsion mechanisms for moving a nanoswimmer using chemical fuel, magnetic fields, ultrasonic pulses and thrust force generated by bacteria in the presence of external stimuli including laser light, and thermal and chemical gradients.

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“…The important qualities desirable for nanorobots are high velocity, efficiency, specificity, controllability and a simple propagation mechanism that can be realized with miniaturized parts. In the realization of nanorobots, other challenges are wearing and friction, significant Brownian motion due to thermal agitation and non rigidity in nano domains due to which it is more propitious to swim or fly compared to crawling and walking [1]. Inspired by the fact that microorganisms existing in nature function expeditiously under these circumstances, scientists and engineers have shown a great interest to conceptualize, model, analyze and make micro-sized swimmers that can move in body fluids [1][2][3][4][5].…”

Section: Introductionmentioning

confidence: 99%

“…In the realization of nanorobots, other challenges are wearing and friction, significant Brownian motion due to thermal agitation and non rigidity in nano domains due to which it is more propitious to swim or fly compared to crawling and walking [1]. Inspired by the fact that microorganisms existing in nature function expeditiously under these circumstances, scientists and engineers have shown a great interest to conceptualize, model, analyze and make micro-sized swimmers that can move in body fluids [1][2][3][4][5]. Efficiency ofpropulsion is extremely low but *Contact author e-mail: nns@bits-piianLac.in is not a cause of concern considering the abundance of energy available to the micro and nano sized biological organisms [2].…”

Section: Introductionmentioning

confidence: 99%

Design and analysis of helical flagella propelled nanorobots

Subramanian

Rathore

Sharma

2009

2009 4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems

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Advancement in the field of nanorobotics has been facilitated by the current advances in nano-bio-technology and nanofabrication methods. The important uses of nanorobots are in advancing medical technology, healthcare and environment monitoring. In bio-medical applications, nanorobots need to swim in biological fluids flowing in narrow channels of few hundred nanometer size. The dominating effects in nanometer size domains are increased apparent viscosity and low Reynolds numbers which makes the design of a propulsion mechanism a challenging task. Micro and nano size biological organisms move by generating planar waves or rotating helical flagella. In the present work, design of propulsion with helical flagella is proposed and a generalized analytical model is developed, simulated and discussed. The performance parameters of the developed model viz. velocity and efficiency have been computed based on resistive force theory and compared with those of the model available in literature. Improved performance, feasibility and generality of the developed flagellar model have been discussed.

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Nanorobot Movement: Challenges and Biologically inspired solutions

Cited by 33 publications

References 79 publications

One Example on How Colloidal Nano- and Microparticles Could Contribute to Medicine

One Example on How Colloidal Nano- and Microparticles Could Contribute to Medicine

Propulsion of an artificial nanoswimmer: a comprehensive review

Design and analysis of helical flagella propelled nanorobots

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