Nanorobotic drug delivery

Zeeshan, Mahira; Shou, Kaiyu; Sivaraman, Kartik M.; Wuhrmann, Thomas; Pellicer, Eva; Nelson, Bradley J.

doi:10.1016/s1369-7021(11)70039-6

Cited by 11 publications

(9 citation statements)

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“…Preparation of Anodic Aluminum Oxide Templates : Anodic aluminum oxide (AAO) templates with a uniform and parallel porous structure were prepared by anodizing an e‐beam evaporated layer of Al (1.5–2 μm thick) on Si substrate with Ti and Au‐seed layers as reported previously 5, 6. A current controlled single‐step anodization was carried out in 0.3 M oxalic acid.…”

Section: Methodsmentioning

confidence: 99%

“…Materials science, pharmacy, engineering and other disciplines have contributed synergistically to the development of nanoscale TDD platforms in several aspects such as nanomaterials synthesis, nanofabrication, motion control, functionalization, drug dosing and triggering methods. A promising approach involves using magnetic nanoagents that can be wirelessly maneuvered by applying external magnetic fields 2–7. This drug targeting strategy could reach confined spaces in the human body to locally deliver therapeutic drugs or molecular vectors.…”

Section: Introductionmentioning

confidence: 99%

“…We demonstrate that Fe NWs are conformally coated by highly crystalline continuous graphitic shells under optimized conditions. The method uses anodic aluminum oxide (AAO) templates on silicon in which Fe NWs are produced by pulsed electrodeposition (PED) (see details on fabrication in the Supporting Information, S1 and S2) 5, 6. Subsequently, the Fe NWs kept in the template are coated with graphite by chemical vapor deposition (CVD).…”

Section: Introductionmentioning

confidence: 99%

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Graphite Coating of Iron Nanowires for Nanorobotic Applications: Synthesis, Characterization and Magnetic Wireless Manipulation

Zeeshan

Pané

Youn

et al. 2012

Adv Funct Materials

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Wireless‐manipulated graphite coated nanomagnets are promising candidates for minimally invasive targeted drug delivery platforms. Iron nanowires coated with graphitic shells are synthesized by template‐assisted deposition. The use of porous aluminum oxide templates enables both the batch production of nanowires by electrodeposition and their subsequent conformal encapsulation in graphite using chemical vapor deposition (CVD). High quality graphitic shells are obtained when CVD conditions are optimized using acetylene as carbon feedstock at 740 °C. Interestingly, the iron nanowires transform into iron carbide during the CVD process leading to changes in magnetic properties. The graphite coated iron nanowires are precisely manipulated against a water flow (0.1 mm/s) using a magnetic field of 350 Oe and a gradient of 50 kOe m−1 in a 5‐DOF magnetic manipulation system. Our approach opens new avenues for the design and synthesis of functional graphite coated nanowires that are promising for nanorobotics applications.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Graphite Coating of Iron Nanowires for Nanorobotic Applications: Synthesis, Characterization and Magnetic Wireless Manipulation

Zeeshan

Pané

Youn

et al. 2012

Adv Funct Materials

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“…Miniaturizing devices to the nanoscale creates a wealth of new possibilities in nanobiotechnology and nanomedicine, such as targeted drug delivery platforms [1]. A nanorobot is a tiny machine, with dimension in nanoscale, designed to perform a specific task.…”

Section: Introductionmentioning

confidence: 99%

“…Nanorobots are used in cancer treatment, target-oriented drug delivery, medical imaging, new sensing devices, information storage devices, new energy systems, super-strong metamaterials, smart windows and walls, ocean-cleaning microsponges, molecular assembler, health sensors, etc. [1][2][3][4][5][6][7][8]. But, the major application of it is in nanomedicine [2].…”

Section: Introductionmentioning

confidence: 99%

Utilization of Nanomaterials in Target Oriented Drug Delivery Vehicles

Mandal

Patait

2021

J. Sci. Res.

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The present investigation deals with the fundamentals of nanorobots, its fabrication, and possible utilization in a different target-oriented drug delivery vehicles. Details of various types of nanorobots and their specific applications are studied in this research. The use of nanorobots in cancer treatment, target-oriented drug delivery, medical imaging, and in new health sensing devices has also been studied. The mechanism of action of nanorobots for the treatment of cancerous cells as well as the formulation and working functions of some recently studied nanorobots are investigated in this work. This paper reviews the research in finding the suitable nanorobotic materials, different fabrication processes of nanorobots, and the current status of application of nanorobots in biomedical, especially in the treatment of cancers. Superparamagnetic iron oxide nanoparticles (SPIONs) have been observed to be used as novel drug delivery vehicle materials. The future perspectives of nanorobots for the utilization in drug delivery are also addressed herewith.

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Emerging Organic and Organic/Inorganic Hybrid Photovoltaic Devices for Specialty Applications: Low‐Level‐Lighting Energy Conversion and Biomedical Treatment

Chen¹

2018

Advanced Optical Materials

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This article reviews the progress made in emerging photovoltaic devices, including dye‐sensitized solar cells, organic solar cells, and perovskite solar cells, for specialty applications. Because they all feature tunable band structures, which can be modified through molecular design and/or altered compositions, the properties of emerging photovoltaic devices can be tailored to fit the special requirements of a particular application. For instance, they can be designed according to the emission spectrum of an artificial light source (e.g., fluorescence lamp and white light‐emitting diode), thereby efficiently converting the indoor lighting to electricity. Furthermore, because there exists a near‐infrared window—ranging from 650 to 1350 nm—in which photons can penetrate deeply into tissues, the absorption bands of these photovoltaic devices can be tailored specially to this therapeutic window to harvest tissue‐penetrating light, thereby wirelessly providing power to biomedical devices positioned beneath the skin. The rapid progress made in these two representative areas suggests further promising applications of such emerging photovoltaic devices.

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Nanorobotic drug delivery

Cited by 11 publications

References 0 publications

Graphite Coating of Iron Nanowires for Nanorobotic Applications: Synthesis, Characterization and Magnetic Wireless Manipulation

Graphite Coating of Iron Nanowires for Nanorobotic Applications: Synthesis, Characterization and Magnetic Wireless Manipulation

Utilization of Nanomaterials in Target Oriented Drug Delivery Vehicles

Emerging Organic and Organic/Inorganic Hybrid Photovoltaic Devices for Specialty Applications: Low‐Level‐Lighting Energy Conversion and Biomedical Treatment

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