Among high-field mobility materials, amorphous indium-gallium-zinc oxide (In-Ga-ZnO) (α-IGZO) has been prominent for their use in thin-film transistors (TFTs). In this Letter, the authors present a novel structure of TFT with tri-active layer (TAL) channel consisting of α-IGZO and In-SnO (ITO) materials. Further, the simulation-based analysis of the proposed device and characteristics in comparison to the single and double active layer channel structures have been reported. This work also analyses the effect of front-back channel thickness-ratios in double-active layer channel TFTs. The proposed TAL channel TFT describes improved switching parameters such as lower threshold voltage (V TH) − 4.24 V, high field-effect mobility (µ FE) 38.4 cm 2 /V-s, moderate subthreshold swing 0.398 mV/decade, and reasonably high ONto OFF current ratio (I ON /I OFF) 0.18 × 10 12. The electrical characteristics persuade the significance of the proposed structure in next-generation flat-panel displays.