In the current paper, the sensitivity performance of functionally graded magneto-electro-elastic (FG-MEE) nanoplate with attached nanoparticles as a nanosensor is analyzed based on nonlocal Mindlin plate assumption. Power law distribution model is employed to display how the material properties of FG-MEE nanoplate vary across the thickness direction. It is supposed that FG-MEE nanoplate is under initial external electric and magnetic potentials. Boundary condition of each edge of FG-MEE nanoplate is assumed to be simply supported. Furthermore, a Pasternak substrate is applied for modelling the total reaction pressure between nanoplate and foundation. Partial differential equations and corresponding boundary conditions are first achieved using Hamilton's variational principle and then analytically solved to determine the frequency shift utilizing Navier's approach. Numerical examples are performed to elucidate the dependency of the sensitivity performance of FG-MEE nanosensor on the volume fraction exponent, nonlocal parameter, total attached mass and location of the nanoparticle, aspect ratio, mode number, initial external electric voltage, initial external magnetic potential, and Pasternak medium coefficients. It is clearly indicated that these factors have highly significant impacts on the variations of frequency shift.