Nanoscale surface coatings and topographies for neural interfaces

Introduction to the RSC Advances themed collection on nano and microscale modifications of biomaterials

“…The most important features include microstructure and topography, nano and micro dimensions, and chemical and phase compositions of the surface layers and coatings. Therefore, research progress in this specic eld can be highly diverse, as demonstrated by the most recent reviews which focus on the nanocomposites of gelatin and various nanoparticles, 1 nano-based biomaterials for leiomyosarcoma therapy, 2 dynamic biomaterials based on material nanoarchitectonics, 3 hydroxyapatite nanoparticles and nanostructured materials, 4 intelligent biomaterials for micro and nanoscale additive manufacturing, 5 nanoscale surface coatings and topographies for neural interfaces, 6 and polymeric drug delivery systems including hydrogels, nanobers, and microspheres. 7,8 In this themed collection, made up of review articles and research papers, the emphasis is rmly placed on the demonstration of links between nano and microscale surface modications, and their effects on mechanical, physical, chemical, and biological properties.…”

In vitro biocompatibility evaluation of functional electrically stimulating microelectrodes on primary glia

“…Other reports document the conjugation of biomolecules onto the surfaces of the electrodes to mask its foreign signature (Eles et al, 2017;Sridar et al, 2017). Antifouling compounds (e.g., zwitterionic polymers, polyethylene glycol) have also been reported in the literature to attenuate acute inflammatory responses elicited against invasive implants (Golabchi et al, 2019;Yang et al, 2020;Gori et al, 2021;Cho et al, 2023;Wu et al, 2023).…”