Nanosecond laser ablation enhances cellular infiltration in a hybrid tissue scaffold

Accelerated tissue regeneration in decellularized vascular grafts with a patterned pore structure

“…25 It was reported that perforation of the decellularized trachea and pericardial tissue improved the cell adherence rate. 28,30 The present study also confirmed rapid infiltration of host cells into the central region of the graft (Fig. 4 and 5a).…”

Adhesion and Growth of Neuralized Mouse Embryonic Stem Cells on Parylene-C/SiO2 Substrates

“…Cell patterning as a research area encompasses multiple techniques to direct cell placement and growth on a variety of 2D and 3D substrates [1]. The use of microcontact printing [2], stencils [3], laser ablation [4] and self-assembled monolayers [5] are invaluable techniques in the fields of tissue engineering, as they facilitate organoid development in biocompatible scaffolds [6,7]. Furthermore, cell patterning has enabled biomaterial evaluation [8] and unlocked new modalities in probing specific tissue development and function [9].…”

Heart on a chip: Micro-nanofabrication and microfluidics steering the future of cardiac tissue engineering

“…Patz et al used excimer laser ablation to directly fabricate channels on agarose, and showed improved attachment, alignment, proliferation and differentiation of C2C12 myoblasts [67]. Similar approaches have been used for the modification of other soft matter [68,69]. The same approach was used by Engelmayr et al for the production of multi-layered elastomeric scaffolds -like honeycomb structure T collagen fibers, as well as to guide the alignment of cells and to replicate the native myocardium tissue microenvironment and anisotropy [70 72] [73].…”