Nanoselenium treatment in fatty liver

Hegedüs, V; Prokisch, József; Fébel, Hedvig; Kleiner, Daniel; Ditrói, K; Szíjártó, Attila; Blázovics, Anna

doi:10.1055/s-0032-1312383

Cited by 6 publications

(4 citation statements)

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“… Physiological effects of selenium. Selenium is known for its antioxidant, antimutagenic and anticarcinogenic properties, it also acts against microbes as well as parasites and has antiinflammatory effects, engages in metabolism, growth and development, protects organs from oxidative stress, affects immune function and improves fertility [ 2 , 47 , 48 , 49 , 50 , 53 , 54 , 60 , 82 , 87 , 104 , 126 , 127 , 128 , 129 , 130 , 131 , 132 , 133 , 134 , 135 , 136 , 137 , 138 ]. …”

Section: Figurementioning

confidence: 99%

A Summary of New Findings on the Biological Effects of Selenium in Selected Animal Species—A Critical Review

Hosnedlová

Kępińska

Skaličková

et al. 2017

IJMS

186

121

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Selenium is an essential trace element important for many physiological processes, especially for the functions of immune and reproductive systems, metabolism of thyroid hormones, as well as antioxidant defense. Selenium deficiency is usually manifested by an increased incidence of retention of placenta, metritis, mastitis, aborts, lowering fertility and increased susceptibility to infections. In calves, lambs and kids, the selenium deficiency demonstrates by WMD (white muscle disease), in foals and donkey foals, it is associated with incidence of WMD and yellow fat disease, and in pigs it causes VESD (vitamin E/selenium deficiency) syndrome. The prevention of these health disorders can be achieved by an adequate selenium supplementation to the diet. The review summarizes the survey of knowledge on selenium, its biological significance in the organism, the impact of its deficiency in mammalian livestock (comparison of ruminants vs. non-ruminants, herbivore vs. omnivore) and possibilities of its peroral administration. The databases employed were as follows: Web of Science, PubMed, MEDLINE and Google Scholar.

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Section: Figurementioning

confidence: 99%

A Summary of New Findings on the Biological Effects of Selenium in Selected Animal Species—A Critical Review

Hosnedlová

Kępińska

Skaličková

et al. 2017

IJMS

186

121

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“…There are some dietary as well as anti-obesity regimes to recover from these diseases, but application of nano-selenium as feed supplement can be effective for fatty liver therapy. Role of nanoscale selenium and its supplementation were studied in male Wistar rats (200–250 g body weight) with fatty liver disease [ 91 ]. The rats were divided into four groups of eight animals each with positive and negative control and fed with and without nano-selenium diet in an experimental regime of 10 days.…”

Section: Reviewmentioning

confidence: 99%

“…In comparison to control, disease group exhibited low level inflammation and free radial release which was validated by transmethylating ability and histological analysis of the samples. This experiment demonstrated the application of bioactive nano-selenium against fatty liver disorder [ 91 ], but more animal trials are required to confirm its therapeutic details.…”

Section: Reviewmentioning

confidence: 99%

Selenium Nanoparticles for Stress-Resilient Fish and Livestock

et al. 2015

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The fisheries and livestock sectors capture the highest share of protein-rich animal food and demonstrate accelerated growth as an agriculture subsidiary. Environmental pollution, climate change, as well as pathogenic invasions exert increasing stress impacts that lead the productivity momentum at a crossroads. Oxidative stress is the most common form of stress phenomenon responsible for the retardation of productivity in fisheries and livestock. Essential micronutrients play a determinant role in combating oxidative stress. Selenium, one of the essential micronutrients, appears as a potent antioxidant with reduced toxicity in its nanoscale form. In the present review, different methods of synthesis and characterization of nanoscale selenium have been discussed. The functional characterization of nano-selenium in terms of its effect on growth patterns, feed digestibility, and reproductive system has been discussed to elucidate the mechanism of action. Moreover, its anti-carcinogenic and antioxidant potentiality, antimicrobial and immunomodulatory efficacy, and fatty acid reduction in liver have been deciphered as the new phenomena of nano-selenium application. Biologically synthesized nano-selenium raises hope for pharmacologically enriched, naturally stable nanoscale selenium with high ecological viability. Hence, nano-selenium can be administered with commercial feeds for improvising stress resilience and productivity of fish and livestock.

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“…Nanoscale selenium has strong effects on the reduction of oxidative stress and it has also been shown that spherical SeNPs have a lower risk of selenium toxicity (Gao et al, 2002). Besides its use as an antioxidant, the immunostimulatory effect of nanoscale selenium has been confirmed (Kojouri et al, 2012;Yazdi et al, 2013) along with its beneficial effects on a number of physiological functions (Hegedüs et al, 2012;Yin et al, 2017). Even more interesting is the fact that SeNPs can be helpful in cancer chemo-prevention as a potential anticancer drug (Chen et al, 2008;Sonkusre et al, 2014) as well as an anticancer drug delivery carrier (Estevez et al, 2014;Liu et al, 2012).…”

Section: Effects and Bioavailability Of Nano-selenium (Senps)mentioning

confidence: 99%

Selenium in the environment

Cappelletti¹,

Funari²,

Gasparotto³

et al. 2021

Environmental Technologies to Treat Selenium Pollution

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Chapter 1 is intended to provide the essential background information to assist operators and researchers who use technologies for the treatment of selenium (Se) in environmental (soils, waters, sediments, air) and biological (foods) samples in addition to analysis of Se-molecular speciation in living organisms (plants, microorganisms, animals and humans). In this regard, it is important to underline that numerous reviews and reports have been published in the last decade on this and related topics (

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Nanoselenium treatment in fatty liver

Cited by 6 publications

References 0 publications

A Summary of New Findings on the Biological Effects of Selenium in Selected Animal Species—A Critical Review

A Summary of New Findings on the Biological Effects of Selenium in Selected Animal Species—A Critical Review

Selenium Nanoparticles for Stress-Resilient Fish and Livestock

Selenium in the environment

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