Nanosensors for health care

Singh, Priyanka; Yadava, R. D. S.

doi:10.1016/b978-0-12-819870-4.00025-6

Cited by 17 publications

(8 citation statements)

References 164 publications

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“…For example, NMs can be used for the safe storage of hydrogen for use as a clean fuel [17]. In nanomedicine, NMs are applied in the mapping and diagnosis of diseases with the so-called "lab-on-a-chip" [18], the arrays of nanosensors [19], magnetic nanoparticles [20], and "quantum dots" [21,22]. Moreover, NMs can be applied as molecular nanostructures to reinforce asphalt and concrete [23,24].…”

Section: Introductionmentioning

confidence: 99%

Nanotoxicology and Nanosafety: Safety-by-Design and Testing at a Glance

Zielińska

Costa

Ferreira

et al. 2020

IJERPH

146

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This review offers a systematic discussion about nanotoxicology and nanosafety associated with nanomaterials during manufacture and further biomedical applications. A detailed introduction on nanomaterials and their most frequently uses, followed by the critical risk aspects related to regulatory uses and commercialization, is provided. Moreover, the impact of nanotoxicology in research over the last decades is discussed, together with the currently available toxicological methods in cell cultures (in vitro) and in living organisms (in vivo). A special focus is given to inorganic nanoparticles such as titanium dioxide nanoparticles (TiO2NPs) and silver nanoparticles (AgNPs). In vitro and in vivo case studies for the selected nanoparticles are discussed. The final part of this work describes the significance of nano-security for both risk assessment and environmental nanosafety. “Safety-by-Design” is defined as a starting point consisting on the implementation of the principles of drug discovery and development. The concept “Safety-by-Design” appears to be a way to “ensure safety”, but the superficiality and the lack of articulation with which it is treated still raises many doubts. Although the approach of “Safety-by-Design” to the principles of drug development has helped in the assessment of the toxicity of nanomaterials, a combination of scientific efforts is constantly urgent to ensure the consistency of methods and processes. This will ensure that the quality of nanomaterials is controlled and their safe development is promoted. Safety issues are considered strategies for discovering novel toxicological-related mechanisms still needed to be promoted.

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Section: Introductionmentioning

confidence: 99%

Nanotoxicology and Nanosafety: Safety-by-Design and Testing at a Glance

Zielińska

Costa

Ferreira

et al. 2020

IJERPH

146

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“…The advantages of cantilever biosensors are widely discussed in literature. These are mainly the capability for label-free detection, miniature size, portability, real time detection, on-chip integration, mass scale production and low cost application [36,[86][87][88].…”

Section: Discussionmentioning

confidence: 99%

Stochastic resonance induced performance enhancement of MEMS cantilever biosensors

Singh

Yadava

2020

J. Phys. D: Appl. Phys.

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This paper presents an application of stochastic resonance for improving the performance of micro-electromechanical system (MEMS) cantilever biosensors operating in liquid media. The hydrodynamic influences in liquid media that consist of added mass effect, viscous damping and squeeze film damping deteriorate the Q-factor of cantilever oscillator sensors so much that their operation under fluid-immersed conditions becomes impractical. The stochastic resonance can be produced by the addition of noise in two ways: one, by direct transfer of noise energy through some nonlinear interaction process with the oscillator; and second, by making intrinsic parameters of the oscillator noisy. In this work, we are concerned with the second approach where MEMS controlled feedback oscillator is the biosensor. The cantilever motion is modeled as a damped harmonic oscillator with its natural frequency and damping coefficient parameters made noisy for generating stochastic resonance. Both the frequency and the damping noises generate stochastic resonance in the oscillator amplitude; however, the damping noise generates an additional resonance effect in the oscillator phase. The latter creates the possibility for improving Q-factor against the detrimental influences of hydrodynamic loading. This is a novel feature, which we explore in this paper for maintaining self-sustained cantilever oscillations in a liquid medium and for enhancing biosensor performance. The biosensor model takes into account the circuit loading effect and the influence of cantilever noise in hydrodynamic environment as well. The analytical relations for mass sensitivity and limit of detection have been obtained. The limit of detection is found to be inversely proportional to where and denote cantilever amplitude and Q-factor, respectively. That means the phase stochastic resonance produced by the addition of damping noise lowers the limit of detection by enhancing both and . A prototype theoretical analysis with a Si-MEMS cantilever ( μm3 dimensions and 10 μm gap from boundary wall) oscillator sensor in aqueous medium shows 2 to 3 orders of magnitude enhancement in the Q-factor and 4 to 5 orders of magnitude improvement in the limit of mass detection.

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“…To get a better understanding of the sensor structure, we discussed the sensor's parts in brief. A nanosensor is a device that incorporates nanomaterials and is used in a variety of applications, including health care, [ 14 ] agriculture, [ 15 ] environmental monitoring, [ 16 ] food science, [ 17 ] biotechnology, and chemical industries. Nanosensors possess three main components: a recognition element, a transducer, and electronics.…”

Section: Nanosensor: Basic Structure and Working Principlementioning

confidence: 99%

Advanced Wearable Sensing Technologies for Sustainable Precision Agriculture – a Review on Chemical Sensors

Muthumalai,

Gokila,

Haldorai

et al. 2023

Advanced Sensor Research

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Crop production is impacted by increased plant diseases and shifting environmental circumstances. Monitoring plant health is necessary to raise crop quality and productivity to meet population growth demands. Nanotechnology‐based sensor platforms provide real‐time plant monitoring capabilities, going beyond the constraints of conventional sensor technologies. Wearables are an evolving area of health monitoring and have been modified for agricultural purposes. Wearable sensors are placed on various plant organs in the agricultural industry to check the crops’ health continuously. The varieties of wearable sensor materials and their fabrications, followed by their sensing mechanisms, are highlighted in this review. Furthermore, monitoring plant micro‐environmental factors, including salinity, hazardous gases, and pesticides, are discussed. This text covers various internal plant growth factors monitoring, such as sap flow, transpiration, and signal monitoring. The challenges of wearable sensors in agriculture are mentioned toward the end.

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Nanosensors for health care

Cited by 17 publications

References 164 publications

Nanotoxicology and Nanosafety: Safety-by-Design and Testing at a Glance

Nanotoxicology and Nanosafety: Safety-by-Design and Testing at a Glance

Stochastic resonance induced performance enhancement of MEMS cantilever biosensors

Advanced Wearable Sensing Technologies for Sustainable Precision Agriculture – a Review on Chemical Sensors

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