Nanostructured Lipid Carrier Technology to Enhance Natural Extracts Delivery: Potential of Skin Regeneration

Abstract

Natural extracts (EXTR) have been proven to effectively regenerate tissues however may need long treatment periods. Here in this study, we investigated curcumin (CURC) and Propolis (PROP) encapsulated in the form of nanostructure lipid carrier (NLC) form. The results have shown that this technology has preserved a higher flavonoid content compared to crude EXTR from both materials under investigation. Interestingly, phenolic content in PROP NLC was significantly higher than EXTR, however, CURC NLC did not show the same pattern compared to its relative EXTR. Further investigations are needed to prove the efficacy of this PROP and CURC NLC as antioxidant, antibacterial and wound healing proficiency.