Nanostructured semiconductor based biochemical sensors

Abstract

Nanostructured materials possess better tunability of their properties compared to their bulk counterparts. These properties have opened up new avenues for fabricating highly sensitive, miniaturised and cost effective sensing devices. For the realisation of a rapid and easy to use immunosensor, nanostructured porous silicon/polyaniline heterostructure has been prepared electrochemically which provides label free, real time electrical detection with high sensitivity for biomolecules (mouse IgG/goat antimouse IgG) from whole serum. Nanostructured thin film SnO 2 sensors prepared by Langmuir Blodgett technique has been investigated for room temperature gas sensing under various chemically polluting ambiances (NH 3 , H 2 S, SO 2 , CO, H 2 , NO 2 and CH 4 ) using electrochemical methods which were able to detect specific gases at room temperature in the presence of other residual gases.

Morphological characteristics of polymeric nylon‐6 film as biological recognition interface for electrochemical immunosensor application

“…Under such a scenario, immunosensor has emerged as a potential detection system for an effective monitoring of pathogen, [3][4][5][6][7][8] contaminant, and toxic material [9][10][11] in the biotechnology applications . 12,13 The effectiveness of biomolecule immobilization strongly depends on the thin film material (the support platform) 14,15 that provides excellent stability, fast lateral wicking speed and reduces biomolecule desorption. 16 Moreover, the thin film material should be insoluble in water and has a high binding capacity to the specifically targeted biomolecules.…”