Nanotechnology Advances in Diagnostics, Drug Delivery, and Regenerative Medicine

Pharmaceutical Nano-Delivery Systems: A Review

“…Nano technology expected to have substantial applications in medicine in disease diagnostics and therapeutics. nano delivery systemes have become well appreciated in the last years where utilizing of nanostructures as delivery agents through incorporation of the drugin the nanocarriersor adsorption on them which promote high specificity and selectivityfor drug localization and targeting 6,7 . The first generation of nanoparticlebased drug delivery systems which are lipid based systems such as solid-lipid nanoparticles, liposomes and micelles 8,9,10 .Nanostructures delivery systems help to deliverdrugs of low water-solubility and/or even low drug oral bioavailability and targeting it to the specified siteaction which lead to reduce dose required, enhance drug efficacy, decrease toxicity, decrease drug resistance, decrease patient to patient drug effect variability and increase the stability of the drug and formulation 11 .Nanostructures stay in the blood circulatory system for a prolonged period and enable the release of drug as per the specified dose.…”

Promoting the bench-to-bedside translation of nanomedicines

“…Since its emergence in the late 1980s, nanotechnology has shown vast potential in biological medicine fields, including drug delivery, diagnostics, and tissue regeneration [ 1 ]. Owing to the enhanced permeability and retention (EPR) effect of solid tumors discovered over 30 years ago [ 2 ], nanomedicines have mostly been developed for cancer diagnosis and therapy, and few of them have been applied clinically [ 3 ].…”