Nanotechnology development in surgical applications: recent trends and developments

Abstract

This paper gives a detailed analysis of nanotechnology's rising involvement in numerous surgical fields. We investigate the use of nanotechnology in orthopedic surgery, neurosurgery, plastic surgery, surgical oncology, heart surgery, vascular surgery, ophthalmic surgery, thoracic surgery, and minimally invasive surgery. The paper details how nanotechnology helps with arthroplasty, chondrogenesis, tissue regeneration, wound healing, and more. It also discusses the employment of nanomaterials in implant surfaces, bone grafting, and breast implants, among other things. The article also explores various nanotechnology uses, including stem cell-incorporated nano scaffolds, nano-surgery, hemostasis, nerve healing, nanorobots, and diagnostic applications. The ethical and safety implications of using nanotechnology in surgery are also addressed. The future possibilities of nanotechnology are investigated, pointing to a possible route for improved patient outcomes. The essay finishes with a comment on nanotechnology's transformational influence in surgical applications and its promise for future breakthroughs. Graphical Abstract

Possibilities of local effect the healing of small bowel sutures in a rat model of acute intra-abdominal infection

“…The decrease in the activity of protein oxidation in the research group, under the same other conditions of the experiment in both groups, can be explained by the local effect of the inhibitor of oxidation reactions used in the ligatures. The increased activity of protein oxidation can disrupt the regeneration [26]. This could possibly account for the findings observed in the histological examination of the control group -the gaps between the fibers of the ligatures and the channel formed by the ligatures.…”

“…The presented way of influencing the regeneration of a sutured wound of the bowel wall and other similar known ways [18][19][20][21][22][23][24]26,27] are aimed at optimizing regeneration processes. The advantage of such ways, including ours, over ways based on the modification of bowel sutures [3,15,16,20] is that the regression of inflammation is accelerated, and the formation of connective tissue is stimulated.…”

“…It is not surprising that many researchers are dedicated to exploring alternative methods for enhancing bowel suture regeneration. Such research primarily concerns the modification of the ligature's material using nanotechnology [25,26]. The modification of ligatures makes it possible to deliver various components affecting regeneration directly to the suture zone.…”

Targeting ferroptosis for leukemia therapy: exploring novel strategies from its mechanisms and role in leukemia based on nanotechnology

“…Nanotechnology is a nanometer-scale configuration of material composition, thereby manipulating their characteristics [ 277 ]. The standard sizing of nanomaterial particle design lies between 1 and 100 nm.…”

Pioneering nanomedicine in orthopedic treatment care: a review of current research and practices

“…The increased surface area of nanoengineered grafts allowed greater interaction between the host bone and the graft surface, opening the way to dependable and anticipated osteointegration, thereby lengthening the lifespan of implants. ( Guarino et al, 2019 ; Abaszadeh et al, 2023 ).…”