Nanotechnology enabled management approaches against the Covid-19 pandemic

Abstract

COVID-19 has been the causative virus for one of the biggest pandemic in human history and is still a major threat to human health after more than a year of its first incidence. Since its outbreak, it fueled a worldwide demand for the following: i) rapid, predictive and sensitive diagnostic tool ii) specific vaccine candidate and targeted prevention iii) effective anti SARS CoV2 therapy and personalized medicine. Different fields of science and technology have contributed in this battle against coronavirus. Nanotechnology has also played a crucial role in making technologically advanced equipment and devices, breaking bottlenecks in facing the pandemic. Deeper insights regarding interface between nanotechnology and coronavirus can further direct the scientists and researchers towards a new era for the impeccable design and repurposing of drugs, vaccines and detection method for COVID-19. Entering the era of Nanotechnology-SARS CoV2 interface will not only be critical in counteracting COVID-19 but also be vital in the management of future pandemics. Hence, our review systematically correlated the SARS-CoV2 structure, life cycle and proteomic antigenicity with the potential drugs, vaccines, diagnostic and management strategies with a special emphasis on the existing and promising role of nanotechnology. This review offers a reference for future studies and guide researchers for the translation of nanotechnological concepts into effective theranostic and management strategies and support our fight against the current and the future coronavirus pandemics.