Nanotechnology in Dentin Disinfection: Can We Preserve the Bond?

Abstract

Aims The aim of the present study is to evaluate the effect of cavity disinfection with 2% chlorhexidine (CHX) and Ag-Au nanoparticles on microleakage and resin tag penetrability of composite restoration under in vitro conditions. Materials and methods Twenty-five human permanent molars extracted for therapeutic reasons were used in the study. Class V cavity of standard dimension was prepared on the buccal and lingual surfaces of the teeth. The teeth were randomly allocated into two groups based on the cavity disinfectant used; group I being 2% chlorhexidine gluconate (chlorhexidine FGM) and group II being cavity disinfectant containing Ag-Au nanoparticles (nanocare gold). In both the groups, the dentin was etched with 37% phosphoric acid and cavity disinfectants were applied following which dentine bonding agent and composite resin were applied and cured. The specimens were then viewed under stereomicroscope and scanning electron microscope for evaluation of microleakage and resin tag formation, respectively. Results The results were statistically analyzed using independent ‘t’ test. No significant difference was seen between the two groups with respect to the microleakage and resin tag penetration values ( p >0.05). Conclusion Cavity disinfectant containing Ag-Au nanoparticles had no effect on the sealing ability and resin tag penetrability of composite resin in permanent molars when compared with 2% CHX. Clinical significance Use of Cavity disinfectant containing Ag-Au nanoparticles with etch and rinse system can be preferred as it satisfies the ideal property of a cavity disinfectant which includes excellent antimicrobial action and non-detrimental effect on the sealing ability and resin tag penetrability. How to cite this article Ramasetty PA, Tripathi AP, Sugandhan S, Naik SV, Deepak BM. Nanotechnology in Dentin Disinfection: Can We Preserve the Bond? Int J Clin Pediatr Dent, 2018;11(6):468-473

Self-Etch Adhesive-Loaded ZrO2/Ag3PO4 Nanoparticles on Caries-Affected Dentin: A Tensile Bond Strength, Scanning Electron Microscopy, Energy Dispersive X-ray Spectroscopy, Survival Rate Assessment of S. mutans, and Degree of Conversion Analysis

“…Recently, the combination of zirconia/silver phosphate (ZrO 2 /Ag 3 PO 4 ) nanoparticles (NPs) has piqued the interest of researchers, primarily because of the synergistic benefits that silver and zirconium NPs offer [9]. In the realm of medical and pharmaceutical nanoengineering, silver nanoparticles (AgNPs) have garnered considerable attention due to their remarkable ability to effectively combat a wide spectrum of bacteria while exhibiting relatively low cytotoxicity when compared to other metal nanoparticles [10][11][12][13]. The available scientific literature has underscored the potential of Ag 3 PO 4 (silver-phosphate) to eliminate both bacteria and fungi.…”