Nanotheranostic Trojan Horse for visualization and photo-immunotherapy of multidrug-resistant bacterial infection
Xin Pang,
Haohang Xu,
Qishun Geng
et al.
Abstract:Effective diagnosis and therapy for bacterial infections, especially those caused by multidrug-resistant (MDR) species, greatly challenge current antimicrobial stewardship. Monocytes, which can chemotactically migrate from the blood to infection site and elicit a robust infection infiltration, provide a golden opportunity for bacterial theranostics. Here, a nano-Trojan Horse was facilely engineered using mannose-functionalized manganese-eumelanin coordination nanoparticles (denoted as MP-MENP) for precise two-… Show more
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