Nanotherapeutics in Skin Therapy

Abstract

Nanotherapeutics has emerged from nanotechnology applications and has a wide range of utilities in the medical field. Nanotherapeutics made a revolutionary change in healthcare and provided a vision to augment diagnostics and treatment solutions by managing the release of contained bioactive compounds. It has gained much research interest in today’s modern world due to its implications in drug delivery and genes, which overcome lacunae prevailing in the existing therapeutic sphere by the use of engineered nanostructures and nanodevices. The interaction of nanostructures with the skin tissue at the subatomic level has significant applications in the diagnosis and treatment of dermatological conditions, especially wound healing and cosmeceutical treatment. Nanotherapies and diagnostics have the potential to improve treatment effectiveness while reducing or eliminating toxicity problems. This book chapter provides an overview of the latest advancements and applications of nanotherapeutics in skin therapy. Nanoparticles, owing to their unique physicochemical properties, have shown immense potential in enhancing drug delivery, improving skin penetration, and targeting specific cellular and molecular pathways implicated in various skin conditions. Key topics covered include the design and synthesis of nanoparticles for skin delivery, including liposomes, polymeric nanoparticles, solid lipid nanoparticles, and nanoemulsions. These nanocarriers can encapsulate a wide range of therapeutic agents, including anti-inflammatory drugs, antimicrobials, antioxidants, and gene-based therapies, enabling precise and controlled release at the site of action.