Nanotoxicological investigations of cocoa pod husk extract-mediated silver nanoparticles in selected tissues of albino rats

Salau, Amadu Kayode; Osineye, S. O.; Lateef, Agbaje

doi:10.1007/s13530-022-00129-6

Cited by 4 publications

(2 citation statements)

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“…Aspartate aminotransferase activities of birds on the various injectables on the other hand were significantly higher than what was obtainable for birds on both the positive and the negative control. Contrarily, Salau et al [1] reported a significantly reduced serum AST in rats treated intraperitoneally with cocoa pod husk extract-mediated silver nanoparticles (CPHE-AgNPs).…”

Section: Cellular Enzymes Of Birds On the Various Injectablesmentioning

confidence: 99%

“…Nanotechnology involves the multidisciplinary field of biotechnology that handles the understanding and control of matter at nanoscale, where an unusual phenomenon enables originative applications. Nanoparticles of both metallic and non-metallic origin have recently been investigated and developed for use in a variety of biochemical and therapeutic disciplines [1]. Biochemically significant metals create concern since they are in harmony with the living organism's system in terms of absorption, assimilation, excretion, and side effects.…”

Section: Introductionmentioning

confidence: 99%

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2022

Nano Plus: Sci. Tech. Nanomat.

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This study investigated the effect of injection of glucose and magnesium oxide nanoparticles (MgONPs) on performance (weight gain and feed conversion ratio) and biochemical parameters (superoxide dismutase -SOD, malondialdehyde -MDA, alkaline phosphatase -ALP, transaminases -alanine transaminase and aspartate aminotransferase) and catalase -CAT in broiler chicks. A total of 105 day-old broiler chicks were randomly distributed into seven treatments (T1 -T7) with three replicates of five birds per replicate. Each treatment group was subcutaneously injected at day old with the following: T1 (without injection -control group), T2 (0.5 mL deionized water -sham group), T3 (100 mg of glucose dissolved in 0.5 mL of deionized water), T4 (100 mg of glucose and 4 mg of magnesium sulphate each dissolved in 0.5 mL of deionized water), T5 (100 mg glucose and 4 mL magnesium oxide nanoparticles solution each dissolved in 0.5 mL of deionized water), T6 (4 mg of magnesium sulphate only dissolved in 0.5 mL of deionized water) and T7 (4 mL of magnesium oxide nanoparticles solution only in 0.5 mL of deionized water). The results of this study showed that in vivo administration of magnesium oxide nanoparticles (at day old) favoured the eventual feed conversion ratio and final weight gain (1.82, 40.10 g, respectively) of the broiler birds when compared with similar values for birds without the nanoparticle injection (2.37, 33.32 g, respectively). It equally revealed that administration of the nanoparticles singly or in addition to glucose posed no detrimental effect (p>0.05) on the tissue enzymes activities of the birds when compared with the control values. Administration and dosage of the nanoparticles have to be keenly monitored in order not to have a detrimental effect on the antioxidant enzymes parameters.

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Section: Cellular Enzymes Of Birds On the Various Injectablesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%