“…[240] In this regard, different technologies can be implemented to bridge this gap, including ultracentrifugation/gradient techniques, sizeexclusion chromatography, ultrafiltration, microfluidics chips, ultimately improving the quality (i.e., size, density, potential, and biochemical composition), and the yield of EVs. In particular, novel technologies based on innovative 1D [241][242][243][244] and 2D materials [245][246][247] may largely facilitate the capture, detection, quantification and quality control of purified EVs, helping to gain a larger foothold in the healthcare and nanomedicine market.…”