Nanozyme Applications: A Glimpse of Insight in Food Safety

Wu, Long; Zhou, Shuhong; Wang, Gonglei; Yun, Yong‐Huan; Liu, Guozhen; Zhang, Wei Min

doi:10.3389/fbioe.2021.727886

Cited by 53 publications

(15 citation statements)

References 119 publications

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“…Different nanoenzyme and nanopore techniques were described as powerful analytical tools for food contaminant detection [ 265 , 266 ]. The concept of enzyme-mimetic nanomaterials is diverse in types of analytes.…”

Section: Other Nanomaterial-based Methodologymentioning

confidence: 99%

Recent Progress in Nanotechnology-Based Approaches for Food Monitoring

et al. 2022

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Throughout the food supply chain, including production, storage, and distribution, food can be contaminated by harmful chemicals and microorganisms, resulting in a severe threat to human health. In recent years, the rapid advancement and development of nanotechnology proposed revolutionary solutions to solve several problems in scientific and industrial areas, including food monitoring. Nanotechnology can be incorporated into chemical and biological sensors to improve analytical performance, such as response time, sensitivity, selectivity, reliability, and accuracy. Based on the characteristics of the contaminants and the detection methods, nanotechnology can be applied in different ways in order to improve conventional techniques. Nanomaterials such as nanoparticles, nanorods, nanosheets, nanocomposites, nanotubes, and nanowires provide various functions for the immobilization and labeling of contaminants in electrochemical and optical detection. This review summarizes the recent advances in nanotechnology for detecting chemical and biological contaminations in the food supply chain.

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Section: Other Nanomaterial-based Methodologymentioning

confidence: 99%

Recent Progress in Nanotechnology-Based Approaches for Food Monitoring

et al. 2022

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“…Nanozyme-based aptasensors are intensively studied in food safety areas, as is evidenced by a dramatic increase in the number of research articles in the past few years. Due to the extraordinary properties of nanozymes and aptamer, the integration of various nanozymes into aptasensors has significantly improved analytical performance, including sensitivity, selectively, and reproducibility [ 121 ]. Compared with conventional ELISA, nanozyme-based aptasensors had some advantages, including high sensitivity and stability and low cost.…”

Section: Conclusion and Perspectivementioning

confidence: 99%

Regulation Mechanism of ssDNA Aptamer in Nanozymes and Application of Nanozyme-Based Aptasensors in Food Safety

Wang

Zhou

et al. 2022

Foods

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Food safety issues are a worldwide concern. Pathogens, toxins, pesticides, veterinary drugs, heavy metals, and illegal additives are frequently reported to contaminate food and pose a serious threat to human health. Conventional detection methods have difficulties fulfilling the requirements for food development in a modern society. Therefore, novel rapid detection methods are urgently needed for on-site and rapid screening of massive food samples. Due to the extraordinary properties of nanozymes and aptamers, biosensors composed of both of them provide considerable advantages in analytical performances, including sensitivity, specificity, repeatability, and accuracy. They are considered a promising complementary detection method on top of conventional ones for the rapid and accurate detection of food contaminants. In recent years, we have witnessed a flourishing of analytical strategies based on aptamers and nanozymes for the detection of food contaminants, especially novel detection models based on the regulation by single-stranded DNA (ssDNA) of nanozyme activity. However, the applications of nanozyme-based aptasensors in food safety are seldom reviewed. Thus, this paper aims to provide a comprehensive review on nanozyme-based aptasensors in food safety, which are arranged according to the different interaction modes of ssDNA and nanozymes: aptasensors based on nanozyme activity either inhibited or enhanced by ssDNA, nanozymes as signal tags, and other methods. Before introducing the nanozyme-based aptasensors, the regulation by ssDNA of nanozyme activity via diverse factors is discussed systematically for precisely tailoring nanozyme activity in biosensors. Furthermore, current challenges are emphasized, and future perspectives are discussed.

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“…Also, the shape, diameter, and functional groups on the nanomaterials influence their enzyme-like activity. 33 As a result, nanozymes are promising for developing analytical techniques for detecting food and clinical biomarkers. 17 Hence, when combined with conventional methods like electrochemical and colourimetric methods, we can achieve sensing methods with high sensitivity and selectivity.…”

Section: Introductionmentioning

confidence: 99%