Nanozyme-based dual-signal sensing system for colorimetric and photothermal detection of AChE activity in the blood of liver-injured mice

He, Chang; Ke, Zhenyi; Li, Kai; Peng, Jiasheng; Yang, Qian; Wang, Lixiang; Feng, Guangfu; Fang, Jun

doi:10.1007/s00216-023-04663-1

Cited by 5 publications

(1 citation statement)

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“…CeO 2 nanoparticles (CeO 2 NPs) have gained popularity as a nanozyme due to their biocompatibility and multienzyme-like properties [ 33 ]. For instance, CeO 2 NPs display oxidase-like properties without needing hazardous H 2 O 2 as a co-substrate [ 34 ]. The oxidase activity of naked CeO 2 nanozyme is relatively weak, which limits its use in antibacterial applications to some extent.…”

Section: Introductionmentioning

confidence: 99%

Fluoride-activated photothermal system for promoting bacteria-infected wound healing

Du,

Liu,

Yang

et al. 2023

J Nanobiotechnol

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Although photothermal therapy (PTT) employing nanozymes has shown excellent antibacterial potential, excessive heating generally harms host cells and hinders recovery. Herein, we report an innovative technique for acquiring the programmed temperature by managing the catalytic activity of nanozymes. The photothermal system of CeO2 + F− + TMB can obtain precise photothermal temperature by adjusting the concentration of fluoride ions under near-infrared irradiation. At the optimized photothermal temperature, the photothermal system affords fine photothermal antibacterial treatment with high-efficiency antibacterial effects against Staphylococcus aureus and Escherichia coli in vitro. In vivo wound healing experiments confirm that the system can effectively promote fibroblast proliferation, angiogenesis and collagen deposition with remarkable wound healing efficiency. This strategy offers a novel design concept for creating a new generation of PTT and opens the way for the creation of alternative antibiotics.

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Section: Introductionmentioning

confidence: 99%