Nanozyme-catalyzed cascade reaction enables a highly sensitive detection of live bacteria

Abstract

Accurate and timely detection of bacteria is critically important for the human health, which helps to find out the original source of bacterial infections and prevent diseases spread. Herein, gold...

2,5-Thiophenedicarboxylic Acid Bridging Hexameric CeIII-Substituted Selenotungstate and Its Application for Detecting Mucin 1

“…With the development of science and technology and functional materials, there have been increasing numbers of interdisciplinary articles reported in recent decades. The applications of POMs not only are any longer focused on catalytic, magnetic, and luminescence but also have been extended toward the explorations of enzyme-like activity, electrochemical sensing, etc. − Although POMs with remarkable redox activity have been proven to be potential electrode materials, their application in electrochemical sensors is greatly restricted owing to the shortcomings of poor conductivity. Therefore, some multifunctional composite materials, which combined POMs with metal nanoparticles (NPs), metal–organic frameworks, covalent–organic frameworks, carbonaceous materials, and conducting polymers, were fabricated to take advantage of synergistic effects to improve conductive properties. − The results indicate that the electrochemical sensors of carbon–POM nanomaterials can exhibit a low detection limit, high selectivity, and good antijamming capability.…”

Biomimetic Integrated Nanozyme for Flare and Recurrence of Gouty Arthritis

“…Their popularity stems from high activity levels, cost-effectiveness, and storage stability [11] , [12] , [13] , [14] , [15] . For example, applications include the treatment of antioxidant stress through catalase (CAT) and superoxide dismutase (SOD) activities [16] , [17] , [18] , [19] , [20] , [21] , biosensor detection based on peroxidase (POD) and glucose oxidase (Gox) activity [22] , [23] , [24] , [25] , as well as cancer photokinetics and chemokinetics utilizing CAT and POD activity [26] , [27] , [28] , [29] , [30] . Reactive oxygen species (ROS), including superoxide anion radicals (⋅O 2 − ), hydrogen peroxide (H 2 O 2 ) and hydroxyl radicals (·OH − ), are partially reduced oxygen metabolites with strong oxidative capabilities.…”