Naphthol-based fluorescent sensors for aluminium ion and application to bioimaging

A novel turn on fluorescent probe for the determination of Al3+ and Zn2+ ions and its cells applications

“…However, high concentration of aluminum and zinc ions may cause many serious diseases [5][6][7][8][9]. Over the past decade, based on these metal ions, extensive research has reported that aluminum (III) ions induces a serious threat to public health, when it is in high concentration levels.…”

“…Compared with other analytical methodologies for example ions atomic absorption spectrometry, inductively coupled mass atomic emission spectrometry (ICM-AES), electrochemical assays, inductively coupled plasma optical emission spectroscopy (ICP-OES), ion selective membrane and so on are currently available for regarding the detection of aluminum (III) and zinc (II) ions [8,[14][15][16]. Nevertheless, these methods are not effective applied for the sensing and recognition of environmentally and biologically pertinent metal ions because they are high cost instrumentations, need an extremely trained person, complicated and time consuming procedures and lack of selectivity.…”

Adaptable DNA-Interactive Probe Proficient at Selective Turn-On Sensing for Al3+: Insight from the Crystal Structure, Photophysical Studies, and Molecular Logic Gate

“… 18 In recent years, naphthol and its derivatives were used as brilliant fluorescence chemosensors for Al 3+ and attracted much attention due to their short synthetic steps, high water solubility, noticeable fluorescence quantum yield, and decent photostability. 20 , 21 …”

“Turn-On” Fluorescent Biosensors for High Selective and Sensitive Detection of Al3+ Ion

“…The toxic effects of Al 3+ ions not only affect plants and aquatic ecosystems, but they also affect humans. Long-term exposure to aluminum can cause harm to human bodies and organs including the onset of diseases such as Alzheimer's disease and Parkinson's disease, and memory loss and cardiac arrest (Liao et al, 2013;Chatterjee et al, 2016;Kumawat et al, 2016;Liu et al, 2016) or even threaten life. Aluminum products were listed in the first category of carcinogens as a preliminary list of carcinogens.…”