Naproxen ecotoxicity and biodegradation by Bacillus thuringiensis B1(2015b) strain

Górny, Dorota; Hupert-Kocurek, Katarzyna; Wojcieszyńska, Danuta

doi:10.1016/j.ecoenv.2018.10.067

Cited by 49 publications

(30 citation statements)

References 37 publications

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“…The degradation of naproxen in monosubstrate conditions occurred with a low efficiency. However, the presence of an additional carbon source such as glucose, phenol, 4-hydroxybenzoic acid or 3,4-dihydroxybenzoic acid increased the effectiveness of this process (Górny et al 2019a;Wojcieszyńska et al 2014). Similar results were obtained by Lu et al (2019).…”

Section: Microbial Decomposition Of Naproxensupporting

confidence: 72%

“…The genotoxicity of naproxen at a higher concentration was also observed by Górny et al (2019a). However, this effect was not dose-dependent (Górny et al 2019a).…”

Section: Occurrence Of Naproxen In the Environmentmentioning

confidence: 90%

“…Oxidative stress damaged the genetic material of Hyalella azteca probably via the direct interaction of reactive oxygen species with DNA (Garcia-Medina et al (2015). The genotoxicity of naproxen at a higher concentration was also observed by Górny et al (2019a). However, this effect was not dose-dependent (Górny et al 2019a).…”

Section: Occurrence Of Naproxen In the Environmentmentioning

confidence: 96%

“…After incubation of B1 strain in the presence of naproxen, there was a significant increase in the value of the ratio of saturated and unsaturated fatty acids. The occurrence of the 16:0 iso 3OH fatty acid in bacterial cell membrane may stabilize its structure by interacting with the membrane protein (Górny et al 2019a). The EC 50 values that were estimated for Chlorella vulgaris and Ankistrodesmus falcatus were 40 mg/L after 24 h of exposure to naproxen (Ding et al 2017).…”

Section: Occurrence Of Naproxen In the Environmentmentioning

confidence: 97%

“…A low concentration of naproxen may also inhibit the growth of crustaceans such as Ceriodaphnia dubia after 7 days of exposure (Li et al 2016). Górny et al (2019a) estimated the mean value of the microbial toxic concentration MTC avg , which is equivalent EC 50 on the 1.66 g/L level using the MARA test with model organisms. This value indicated a low toxicity of naproxen for bacteria, which was probably connected with the lack of a proper carrier of naproxen in bacterial cells.…”

Section: Occurrence Of Naproxen In the Environmentmentioning

confidence: 99%

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Naproxen in the environment: its occurrence, toxicity to nontarget organisms and biodegradation

Wojcieszyńska

Guzik

2020

Appl Microbiol Biotechnol

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123

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This article summarizes the current knowledge about the presence of naproxen in the environment, its toxicity to nontarget organisms and the microbial degradation of this drug. Currently, naproxen has been detected in all types of water, including drinking water and groundwater. The concentrations that have been observed ranged from ng/L to μg/L. These concentrations, although low, may have a negative effect of long-term exposure on nontarget organisms, especially when naproxen is mixed with other drugs. The biological decomposition of naproxen is performed by fungi, algae and bacteria, but the only well-described pathway for its complete degradation is the degradation of naproxen by Bacillus thuringiensis B1(2015b). The key intermediates that appear during the degradation of naproxen by this strain are O-desmethylnaproxen and salicylate. This latter is then cleaved by 1,2-salicylate dioxygenase or is hydroxylated to gentisate or catechol. These intermediates can be cleaved by the appropriate dioxygenases, and the resulting products are incorporated into the central metabolism. Key points •High consumption of naproxen is reflected in its presence in the environment. •Prolonged exposure of nontargeted organisms to naproxen can cause adverse effects. •Naproxen biodegradation occurs mainly through desmethylnaproxen as a key intermediate.

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Section: Microbial Decomposition Of Naproxensupporting

confidence: 72%

“…The genotoxicity of naproxen at a higher concentration was also observed by Górny et al (2019a). However, this effect was not dose-dependent (Górny et al 2019a).…”

Section: Occurrence Of Naproxen In the Environmentmentioning

confidence: 90%

Section: Occurrence Of Naproxen In the Environmentmentioning

confidence: 96%

Section: Occurrence Of Naproxen In the Environmentmentioning

confidence: 97%

Section: Occurrence Of Naproxen In the Environmentmentioning

confidence: 99%

See 3 more Smart Citations

Naproxen in the environment: its occurrence, toxicity to nontarget organisms and biodegradation

Wojcieszyńska

Guzik

2020

Appl Microbiol Biotechnol

Self Cite

123

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Green synthesis of metal nanoparticles from Codium macroalgae for wastewater pollutants removal by adsorption

Şahin,

Arslan,

Tomul

et al. 2024

CLEAN Soil Air Water

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Algae have adsorption properties and reducing agents due to their rich content. In this study, palladium nanoparticles (Pd NP), platinum nanoparticles (Pt NP), and iron oxide nanoparticles (Fe3O4 NP) were prepared from Codium macroalgae using green synthesis. The structure of the synthesized nanoparticles was elucidated by X‐ray diffractometry, Fourier transforms infrared spectroscopy, Brunauer–Emmett–Teller analysis, transmission electron microscopy, ultraviolet‐visible spectroscopy and scanning electron microscopy‐energy dispersive X‐ray spectrometry and their use as nanoadsorbents for the removal of pollutants from aqueous media was investigated in detail. Naproxen (NPX), an anti‐inflammatory drug, and the dyes methylene blue (MB) and cresol red (CR) were selected as pollutants for this study. Batch adsorption experiments were conducted using both real wastewater obtained from the Organised Industrial Zone of Isparta Province and synthetic water samples prepared with tap water from Burdur Province and pure water. Under optimum adsorption conditions, Pd NP showed significant efficiency in the real wastewater sample, with an adsorption capacity of 37.19 and 50.03 mg g–1 for CR and NPX, respectively, within 150 min. In comparison, Pt NP showed an adsorption capacity of 40.01 mg g–1 for MB within the same timeframe. These findings indicate that while Pd NP showed the highest adsorption capacity for both CR and NPX, Pt NP showed the highest adsorption capacity for MB. The Langmuir model and the pseudo‐second‐order equation were more suitable to describe the adsorption behavior of CR, MB, and NPX. In addition, studies on the desorption and reusability of the nanoadsorbents were carried out under the same optimum experimental conditions.

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Adsorptive removal of naproxen onto nano magnesium oxide‐modified castor wood biochar: Treatment of pharmaceutical wastewater via sequential Fenton's‐adsorption process

Bano,

Aziz,

Ameen

et al. 2024

IUBMB Life

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This current investigation explored the thermal conversion process of castor wood into biochar, which was subsequently harnessed for removing naproxen from pharmaceutical industrial effluent via adsorption. Surface composition analyses conducted through scanning electron microscopy–energy dispersive X‐ray, laser‐induced breakdown spectroscopy, and Fourier‐transform infrared studies unveiled the presence of nano MgO particles within the adsorbent material. Employing optimization techniques such as response surface methodology facilitated a refined approach to batch study. The optimized conditions for batch naproxen sodium (NPX) adsorption on nano‐MgO‐modified biochar were identified as pH 4, 1.5 g/L adsorbent dosage, and a 120‐min contact time maintaining a constant NPX concentration of 10 mg/L. The adsorption capacity was calculated to be 123.34 mg/g for a nano‐magnesium oxide‐modified castor wood biochar (modified biochar) and 99.874 mg/g for pristine castor wood biochar (pristine biochar). Fenton's reagents comprising 15 mM of FeSO4 (7H2O) and 25 mM of H2O2 have been scrutinized under conditions of pH 3.0, a reaction time of 30 min, a temperature of 30°C, and stirring at 120 rpm, followed by batch adsorption treatment. The COD, NH3–N, NO3−, PO43−, and NPX removal percentages was found to be 90%, 87%, 79%, 80%, and 90%, respectively. Thus nano MgO‐modified biochar holds promise of treatment of pharmaceutical effluent.

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Naproxen ecotoxicity and biodegradation by Bacillus thuringiensis B1(2015b) strain

Cited by 49 publications

References 37 publications

Naproxen in the environment: its occurrence, toxicity to nontarget organisms and biodegradation

Naproxen in the environment: its occurrence, toxicity to nontarget organisms and biodegradation

Green synthesis of metal nanoparticles from Codium macroalgae for wastewater pollutants removal by adsorption

Adsorptive removal of naproxen onto nano magnesium oxide‐modified castor wood biochar: Treatment of pharmaceutical wastewater via sequential Fenton's‐adsorption process

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